Journal of Thrombosis and Haemostasis
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#1Lakshman Vasanthamohan (Lakeridge Health)
#2Kochawan Boonyawat (MU: Mahidol University)H-Index: 10
Last. Mark Crowther (McMaster University)H-Index: 121
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#1Muntadhar Al Moosawi (UBC: University of British Columbia)H-Index: 1
#2Aaron F.J. Iding (UM: Maastricht University)
Last. Caterina Casari (French Institute of Health and Medical Research)H-Index: 17
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#1Sravya Kattula (UNC: University of North Carolina at Chapel Hill)H-Index: 4
#2Yaqiu Sang (UNC: University of North Carolina at Chapel Hill)
Last. Alisa S. Wolberg (UNC: University of North Carolina at Chapel Hill)H-Index: 39
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BACKGROUND Venous thrombosis (VT) and pulmonary embolism (PE), collectively venous thromboembolism (VTE), cause high mortality and morbidity. Factor XIII (FXIII) crosslinks fibrin to enhance thrombus stability and consequently may influence PE risk. Elucidating mechanisms contributing to PE is limited by a lack of models that recapitulate human PE characteristics. OBJECTIVE We aimed to develop a mouse model that permits embolization of red blood cell (RBC)- and fibrin-rich VT and determine the c...
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#1Oliver Königsbrügge (Medical University of Vienna)H-Index: 13
#2Hannah Meisel (Medical University of Vienna)
Last. Wolfgang C. Winkelmayer (BCM: Baylor College of Medicine)H-Index: 74
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BACKGROUND Evidence supporting the use of anticoagulation for the prevention of stroke and thromboembolism in patients with kidney failure on hemodialysis (HD) and atrial fibrillation (AF) is limited. We prospectively assessed the incidences of stroke and major bleeding, as well as anticoagulation strategies in patients on HD with AF. METHODS We recruited 625 prevalent HD patients into a population-based observational cohort study. The primary prospective outcomes were thromboembolic events (str...
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#1Nigel Mackman (UNC: University of North Carolina at Chapel Hill)H-Index: 116
#2Steven P. Grover (UNC: University of North Carolina at Chapel Hill)H-Index: 15
Last. Silvio Antoniak (UNC: University of North Carolina at Chapel Hill)H-Index: 25
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Tissue factor (TF) is induced in a variety of cell types during viral infection, which likely contributes to disseminated intravascular coagulation and thrombosis. TF-expressing cells also release TF-positive extracellular vesicles (EVs) into the circulation that can be measured using an EVTF activity assay. This review summarizes studies that analyze TF expression, TF-positive EVs, activation of coagulation, and thrombosis after infection with influenza A virus (IAV) and coronaviruses (CoVs), i...
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#2Ryohei Kawasaki (Chugai Pharmaceutical Co.)H-Index: 4
Last. Yasushi Yoshimura (Chugai Pharmaceutical Co.)H-Index: 10
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Background null Emicizumab is a humanized bispecific monoclonal antibody that bridges activated factor IX (FIXa) and factor X (FX) to mimic the function of factor VIII (FVIII). It suppresses the bleeding tendency in hemophilia A patients with or without FVIII inhibitors. A case of an adult FVIII inhibitor-positive hemophilia A patient in whom treatment with emicizumab was discontinued owing to the repeated bleeding events and prolonged activated partial thromboplastin time. null Objective null T...
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#1Laura Avila (U of T: University of Toronto)H-Index: 1
#2Nour Amiri (U of T: University of Toronto)H-Index: 3
Last. Leonardo R. Brandão (U of T: University of Toronto)H-Index: 25
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Background null Graduated compression garments (CG) are a standard form of management of post-thrombotic syndrome (PTS) in adults, but data in children are lacking. We aimed to study the attitudes toward CG and change in PTS severity score in children who were prescribed CG for PTS management. null Methods null Children with PTS were enrolled in this longitudinal prospective study at the time of CG prescription. PTS severity was measured at baseline and follow-up using CAPTSure© ; attitude towar...
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