Neurocritical Care
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#1Sebastian Major (Humboldt University of Berlin)H-Index: 22
#2Nenad Gajovic-Eichelmann (Fraunhofer Society)H-Index: 15
Last. Jens P. Dreier (Humboldt University of Berlin)H-Index: 64
view all 4 authors...
BACKGROUND Spreading depolarization (SD) and the initial, still reversible phase of neuronal cytotoxic edema in the cerebral gray matter are two modalities of the same process. SD may thus serve as a real-time mechanistic biomarker for impending parenchyma damage in patients during neurocritical care. Using subdural platinum/iridium (Pt/Ir) electrodes, SD is observed as a large negative direct current (DC) shift. Besides SD, there are other causes of DC shifts that are not to be confused with SD...
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#1Christine A. Meadows (UNM: University of New Mexico)H-Index: 1
#2Herbert Davis (UNM: University of New Mexico)H-Index: 11
Last. Andrew P. Carlson (UNM: University of New Mexico)H-Index: 18
view all 8 authors...
BACKGROUND Chronic subdural hematoma (cSDH) is a common neurosurgical condition responsible for excess morbidity, particularly in the geriatric population. Recovery after evacuation is complicated by fluctuating neurological deficits in a high proportion of patients. We previously demonstrated that spreading depolarizations (SDs) may be responsible for some of these events. In this study, we aim to determine candidate risk factors for probable SD and assess the influence of probable SD on outcom...
2 CitationsSource
#1Brian L. Edlow (Harvard University)H-Index: 27
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#1David Robinson (University of Cincinnati Academic Health Center)
#2Jed A. Hartings (University of Cincinnati Academic Health Center)H-Index: 39
Last. Brandon Foreman (University of Cincinnati Academic Health Center)H-Index: 23
view all 3 authors...
1 CitationsSource
#1David Robinson (UC: University of Cincinnati)H-Index: 1
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#1Lindsey Gurin (NYU: New York University)H-Index: 2
#2Megan Evangelist (NYU: New York University)
Last. Steven L. Galetta (NYU: New York University)H-Index: 32
view all 11 authors...
Early neurorehabilitation improves outcomes in patients with disorders of consciousness (DoC) after brain injury, but its applicability in COVID-19 is unknown. We describe our experience implementing an early neurorehabilitation protocol for patients with COVID-19-associated DoC in the intensive care unit (ICU) and evaluate factors associated with recovery. During the initial COVID-19 surge in New York City between March 10 and May 20, 2020, faced with a disproportionately high number of ICU pat...
1 CitationsSource
#1Inez Koopman (UU: Utrecht University)H-Index: 1
#2Dagmar Verbaan (UvA: University of Amsterdam)H-Index: 27
Last. Féline E. V. Scheijmans (UU: Utrecht University)H-Index: 2
view all 12 authors...
BACKGROUND: In some acute care trials, immediate informed consent is not possible, but deferred consent is often considered problematic. We investigated the opinions of patients, proxies, and physicians about deferred consent in an acute stroke trial to gain insight into its acceptability and effects. METHODS: Paper-based surveys were sent to patients who were randomly assigned in the Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage (ULTRA) trial between 2015 and 2018 in two tertiary re...
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#1Brittany Bolduc Lachance (UMB: University of Maryland, Baltimore)H-Index: 2
#2Zhuoran Wang (UMB: University of Maryland, Baltimore)H-Index: 2
Last. Xiaofeng JiaH-Index: 29
view all 4 authors...
BACKGROUND Science continues to search for a neuroprotective drug therapy to improve outcomes after cardiac arrest (CA). The use of glibenclamide (GBC) has shown promise in preclinical studies, but its effects on neuroprognostication tools are not well understood. We aimed to investigate the effect of GBC on somatosensory evoked potential (SSEP) waveform recovery post CA and how this relates to the early prediction of functional outcome, with close attention to arousal and somatosensory recovery...
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#1John R. Williams (UW: University of Washington)H-Index: 7
#2Edwin Nieblas-Bedolla (UW: University of Washington)H-Index: 3
Last. Sharon J. Durfy (UW: University of Washington)H-Index: 14
view all 15 authors...
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#1Tia Chakraborty (Mayo Clinic)H-Index: 4
#2Sherri A. Braksick (Mayo Clinic)H-Index: 7
Last. Eelco F. M. Wijdicks (Mayo Clinic)H-Index: 103
view all 4 authors...
Status myoclonus (SM) after cardiac arrest (CA) may signify devastating brain injury. We hypothesized that SM correlates with severe neurologic and systemic post-cardiac-arrest syndrome (PCAS). Charts of patients admitted with CA to Mayo Clinic Saint Marys Hospital between 2005 and 2019 were retrospectively reviewed. Data included the neurologic examination, ancillary neurologic tests, and systemic markers of PCAS. Nonsustained myoclonus was clinically differentiated from SM. The cerebral perfor...
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Top fields of study
Neurointensive care
Neurology
Intensive care medicine
Subarachnoid hemorrhage
Anesthesia
Stroke
Medicine