International Journal of Epidemiology
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#1Benjamin Amoah (Lancaster University)H-Index: 6
#2Claudio Fronterre (Lancaster University)H-Index: 11
Last. Peter J. Diggle (Lancaster University)H-Index: 94
view all 11 authors...
BACKGROUND: As the prevalences of neglected tropical diseases reduce to low levels in some countries, policymakers require precise disease estimates to decide whether the set public health targets have been met. At low prevalence levels, traditional statistical methods produce imprecise estimates. More modern geospatial statistical methods can deliver the required level of precision for accurate decision-making. METHODS: Using spatially referenced data from 3567 cluster locations in Ethiopia in ...
#1Louise Mc Grath-Lone (UCL: University College London)H-Index: 6
#2Nicolás Libuy (UCL: University College London)H-Index: 1
Last. Ruth Blackburn (UCL: University College London)H-Index: 14
view all 9 authors...
#1Sara Nejatinamini (U of C: University of Calgary)H-Index: 6
#2Jenny Godley (U of C: University of Calgary)H-Index: 10
Last. Dana Lee Olstad (U of C: University of Calgary)H-Index: 21
view all 9 authors...
BACKGROUND Compared with those with a higher socio-economic position (SEP), individuals with a lower SEP have higher cancer morbidity and mortality. However, the contribution of modifiable risk factors to these inequities is not known. This study aimed to quantify the mediating effects of modifiable risk factors to associations between SEP and cancer morbidity and mortality. METHODS This study used a prospective observational cohort design. We combined eight cycles of the Canadian Community Heal...
#1Rebecca BentleyH-Index: 31
#2Koen SimonsH-Index: 12
Last. Tony BlakelyH-Index: 69
view all 5 authors...
BACKGROUND At the individual level, it is well known that pregnancies have a short-term effect on a woman's cardiovascular system and blood pressure. The long-term effect of having children on maternal blood pressure, however, is unknown. We thus estimated the causal effect of having children on blood pressure among mothers in India, a country with a history of high fertility rates. METHODS We used nationally representative cross-sectional data from the 2015-16 India National Family and Health S...
BACKGROUND Coffee consumption has been associated with a reduced risk of some cancers, but the evidence for renal cell carcinoma (RCC) is inconclusive. We investigated the relationship between coffee and RCC within a large cohort. METHODS Coffee intake was assessed at baseline in the National Institutes of Health-American Association of Retired Persons Diet and Health Study. Among 420 118 participants eligible for analysis, 2674 incident cases were identified. We fitted Cox-regression models to ...
#1Eleni-Rosalina Andrinopoulou (EUR: Erasmus University Rotterdam)H-Index: 16
#2Michael O. Harhay (UPenn: University of Pennsylvania)H-Index: 26
Last. Dimitris Rizopoulos (EUR: Erasmus University Rotterdam)H-Index: 38
view all 4 authors...
Individualized prediction is a hallmark of clinical medicine and decision making. However, most existing prediction models rely on biomarkers and clinical outcomes available at a single time. This is in contrast to how health states progress and how physicians deliver care, which relies on progressively updating a prognosis based on available information. With the use of joint models of longitudinal and survival data, it is possible to dynamically adjust individual predictions regarding patient ...
#1Yi-Qian Sun (NTNU: Norwegian University of Science and Technology)H-Index: 11
#2Rebecca C Richmond (UoB: University of Bristol)H-Index: 32
Last. Lin Jiang (NTNU: Norwegian University of Science and Technology)H-Index: 2
view all 21 authors...
BACKGROUND It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated measurements, and to appraise the putative role of DNA methylation in the pathway between smoking and lung cancer development. METHODS We derived a nested case-control study from the Trondelag Health Study (HUNT), including 140 incident patients who developed lung cancer during 20...
#1Fadlalla G. Elfadaly (OU: Open University)H-Index: 5
#2Alex Adamson (NIH: National Institutes of Health)H-Index: 1
Last. Cosetta Minelli (NIH: National Institutes of Health)H-Index: 52
view all 8 authors...
Motivation null null Combination of multiple datasets is routine in modern epidemiology. However, studies may have measured different sets of variables; this is often inefficiently dealt with by excluding studies or dropping variables. Multilevel multiple imputation methods to impute these ‘systematically’ missing data (as opposed to ‘sporadically’ missing data within a study) are available, but problems may arise when many random effects are needed to allow for heterogeneity across studies. We ...
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