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#1Isabel Witvrouwen (University of Antwerp)H-Index: 3
#2Dominique Mannaerts (University of Antwerp)H-Index: 7
Last. Emeline M. Van Craenenbroeck (University of Antwerp)H-Index: 28
view all 8 authors...
In preeclampsia (PE), pre-existent maternal endothelial dysfunction leads to impaired placentation and vascular maladaptation. The vascular endothelial growth factor (VEGF) pathway is essential in the placentation process and VEGF expression is regulated through post-transcriptional modification by microRNAs (miRNAs). We investigated the expression of VEGF-related circulating miR-16, miR-29b, miR-126, miR-155 and miR-200c in PE vs healthy pregnancies (HPs), and their relation with vascular funct...
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#1Consolato Sergi (WUST: Wuhan University of Science and Technology)H-Index: 32
An imbalance between protein aggregation and protein degradation may induce 'stress' in the functionality of the endoplasmic reticulum (ER). There are quality control (QC) mechanisms to minimize misfolding and to eliminate misfolded proteins before aggregation becomes lethal for the cell. Proper protein folding and maturation is one of the crucial functions of the ER. Chaperones of the ER and folding enzymes guarantee correct conformational maturation of emerging secretory proteins. Histone deac...
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#1Peng Yan (SDU: Shandong University)H-Index: 2
Last. Chuanyong Liu (SDU: Shandong University)H-Index: 9
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#1Daqiu Chen (Fujian Medical University)
#2Yanqing Wu (Fujian Medical University)H-Index: 1
Last. Shunxiang Luo (Fujian Medical University)H-Index: 1
view all 7 authors...
BACKGROUND Suxiao Xintong dropping pills (SXXTDP), a traditional Chinese medicine, is widely applied for treating myocardial infarction (MI). However, its therapy mechanisms are still unclear. Therefore, this research is designed to explore the molecular mechanisms of SXXTDP in treating MI. METHODS The active ingredients of SXXTDP and their corresponding genes of the active ingredients were retrieved from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database. MI-related genes we...
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#1Wei Liu (Lanzhou University)H-Index: 1
#2Qin-Peng Wang (Lanzhou University)H-Index: 1
Last. Jia Guo (Lanzhou University)H-Index: 1
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Background : Several studies demonstrated that long non-coding RNA differentiation antagonizing non-protein coding RNA (lncRNA DANCR) expression might have the potential capacity to predict the cancer prognosis, however, definite conclusion has not been obtained. The aim of this meta-analysis was to evaluate the prognostic value of lncRNA DANCR expression in cancers. Methods : PubMed, Web of Science, Scopus and Embase were comprehensively searched for relevant studies. Studies meeting all inclus...
3 CitationsSource
#1Anze Yu (CSU: Central South University)H-Index: 3
#2Kai Guo (CSU: Central South University)H-Index: 1
Last. Xiongbing Zu (CSU: Central South University)H-Index: 1
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BACKGROUND Evaluation of the feasibility for osteopontin (OPN) to serve as a biomarker in the prognosis and clinical-pathological features of prostate cancer patients. METHODS The original publications related to osteopontin and prostate cancer were comprehensively searched in the online databases, including PubMed, Embase, Cochrane Library, Web of Science, Medline, Wanfang and China National Knowledge Infrastructure up to August 2019. Results were analyzed by Revman 5.3 and Stata 12.0. RESULTS ...
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#1Yen-Jen Chen (Taipei Veterans General Hospital)
#2Ching Shui Huang (TMU: Taipei Medical University)H-Index: 13
Last. Chi-Cheng Huang (Taipei Veterans General Hospital)H-Index: 1
view all 9 authors...
Breast cancer intrinsic subtypes have been identified based on the transcription of a predefined gene expression (GE) profiles and algorithm (prediction analysis of microarray 50 gene set, PAM50). The present study compared molecular subtyping with oligonucleotide microarray and NanoString nCounter assay. A total of 109 Taiwanese breast cancers (24 with adjacent normal breast tissues) were assayed with Affymetrix Human Genome U133 plus 2.0 microarrays and 144 were assayed with the NanoString nCo...
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#1Samuel Chuah (SingHealth)H-Index: 1
#1Samuel Chuah (NUS: National University of Singapore)
Last. Valerie Chew (SingHealth)H-Index: 15
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Uveal Melanoma (UM) is a rare cancer deriving from melanocytes within the uvea. It has a high rate of metastasis, especially to the liver, and a poor prognosis thereafter. Autophagy, an intracellular programmed digestive process, has been associated with the development and progression of cancers, with controversial pro- and anti-tumour roles. Although previous studies have been conducted on autophagy-related genes (ARGs) in various cancer types, its role in UM requires a deeper understanding fo...
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#1Rajesh Ahirwar (ICMR: Indian Council of Medical Research)H-Index: 3
#2Sonu GandhiH-Index: 19
Last. Saroj Kumar (Apeejay Stya University)
view all 9 authors...
Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory infection caused by severe acute respiratory syndrome virus (SARS-CoV-2), a novel human coronavirus. COVID-19 was declared a pandemic by World Health Organization in March 2020 for its continuous and rapid spread worldwide. Rapidly emerging COVID-19 epicenters and mutants of concerns have created mammoth chaos in healthcare sectors across the globe. With over 185 million infections and approximately 4 million deaths globally, ...
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#1Wen Li (SZU: Shenzhen University)
#2Xiaobin Wang (SZU: Shenzhen University)
Last. Wanxia Cai (Southern University of Science and Technology)H-Index: 1
view all 12 authors...
Adenoid cystic carcinoma (ACC) is an extremely rare salivary gland tumor with a poor prognosis and needs attention on molecular mechanisms. Protein ubiquitination is an evolutionarily conserved post-translational modification (PTM) for substrates degradation and controls diverse cellular functions. The broad cellular function of ubiquitination network holds great promise to detect potential targets and identify respective receptors. Novel technologies are discovered for in-depth research and cha...
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