Experimental Gerontology
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Abstract null null Our previous study showed that the water-soluble heteropolysaccharide extracted from Gracilaria lemaneiformis (GLHP) has excellent anti-inflammation and anti-oxidant properties. This study explored the efficacy of GLHP against skin anti-photoaging in human immortalized keratinocytes (HaCaT) cells and BALB/c mice under UVB irradiation. Cell viability, antiapoptotic, reactive oxygen species (ROS) scavenging activity, mitochondrial membrane potential, and cell wound scratch assay...
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#1Inês Amanda Streit (UFAM: Federal University of Amazonas)
#2Suzy S. Pinto (UFAM: Federal University of Amazonas)
Last. Ewertton de Souza Bezerra (UFAM: Federal University of Amazonas)H-Index: 5
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Abstract null null The aim of this study was to analyze the effects of multicomponent training with body weight on functional capacity response and power in aging persons. Twenty-seven active older women were assigned for convenience to control (active CG) or multicomponent training groups (MTG). The two groups exercised for 10 weeks, the active CG carried out the usual activities of the community service program, while the MTG followed a multicomponent training program. The countermovement and ...
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#1Huihui Xi (JLU: Jilin University)
#2Yayu He (JLU: Jilin University)H-Index: 1
Last. Yuan Yuan (JLU: Jilin University)
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Abstract null null Objective null The purpose of this study is to evaluate the effects of combined aerobic and resistance exercise on blood pressure (BP) in postmenopausal women. The results of this study will provide an effective means for postmenopausal women to control BP and reduce the morbidity and mortality of cardiovascular disease (CVD). null null null Methods null Eligible studies were searched in five electronic databases until November 2020, and 11 randomized controlled trials that me...
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#1Emerson Santiago (Yale University)
#2David F. Moreno (Yale University)H-Index: 6
Last. Murat Acar (Yale University)H-Index: 13
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Aging is a complex phenomenon of functional decay in a biological organism. Although the effects of aging are readily recognizable in a wide range of organisms, the cause(s) of aging are ill defined and poorly understood. Experimental methods on model organisms have driven significant insight into aging as a process, but have not provided a complete model of aging. Computational biology offers a unique opportunity to resolve this gap in our knowledge by generating extensive and testable models t...
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#1James L. Dorling (Pennington Biomedical Research Center)
#2Daniel W. Belsky (Columbia University)H-Index: 44
Last. Michael S. Kobor (UBC: University of British Columbia)H-Index: 65
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Abstract null null Caloric restriction (CR) improves markers of aging in humans; but it is not known if the fat mass and obesity-associated gene (FTO) rs9939609 single nucleotide polymorphism (SNP), which is associated with appetite and energy intake, influences adherence to prolonged CR. Utilizing data from the two-year Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE™) phase 2 randomized controlled trial, we tested whether the FTO rs9939609 SNP was associated...
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#1Israel S. Ribeiro (UFBA: Federal University of Bahia)H-Index: 3
#2Ítalo Sousa Pereira (UFBA: Federal University of Bahia)H-Index: 4
Last. Robson Amaro Augusto da Silva (UFBA: Federal University of Bahia)H-Index: 7
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Abstract null null The aim of this study was to assess the influence of physical activity in inflammatory, biochemical and endocrine parameters of middle-aged and elderly men with Systemic Arterial Hypertension (SAH) and Type 2 Diabetes Mellitus (T2DM). The assessment was comprised by 77 male volunteers aged between 45 and 59 years old (middle-aged men) or 60 to 86 years old (elderly men), diagnosed with SAH and T2DM, assisted by Family Health Units in Vitoria da Conquista, Bahia, Brazil. Accord...
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#1S. V. Logvinov (Siberian State Medical University)H-Index: 7
#2N. V. Naryzhnaya (RAS: Russian Academy of Sciences)H-Index: 6
Last. Peter R. Oeltgen (UK: University of Kentucky)H-Index: 22
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Abstract null null Background null Age and diabetes are risk factors for arterial hypertension. However, the relationship between age, connective tissue growth factors, vascular aging and arterial hypertension while on a the high-carbohydrate high-fat diet (HCHFD) remains poorly understood. null null null Purpose null To estimate the relationship between humoral factors, the morphological changes of aorta and impaired blood pressure regulation under the influence of age and a HCHFD. null null nu...
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#1Karla Minacca Osco (UNESP: Sao Paulo State University)
#2Francesco CampaH-Index: 12
Last. Luis Alberto Gobbo (UNESP: Sao Paulo State University)H-Index: 14
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Abstract null null The present study aimed to investigate the effects of traditional resistance training compared to elastic tubes training on bioimpedance vector patterns, body composition, and strength in older women. Thirty-eight older women (age 68.7 ± 6.9 years, body mass index 28.8 ± 7.2 kg/m2) were randomly assigned to perform traditional resistance or elastic tubes training three times per week for 12 weeks. Body composition was assessed by dual energy X-ray absorptiometry and bioelectri...
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#1Ianire Maté (Complutense University of Madrid)H-Index: 9
#2Irene Martínez de Toda (Complutense University of Madrid)H-Index: 10
Last. Mónica De la Fuente (Complutense University of Madrid)H-Index: 52
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Abstract null null Chronic obstructive pulmonary disease (COPD) is characterised by inflammatory and oxidative alterations in the lung and extrapulmonary compartments, through involvement of the immune system. Several leukocyte functions are health markers and good predictors of longevity, and high pro-inflammatory and oxidative states are related to more aged profiles. Here, we aimed to investigate the aging rate in terms of immunosenescence in COPD men with respect to healthy age-matched contr...
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#1Martin Těšický (Charles University in Prague)H-Index: 3
#2Tereza Krajzingrova (Charles University in Prague)
Last. Tomáš Albrecht (CAS: Academy of Sciences of the Czech Republic)H-Index: 28
view all 11 authors...
Abstract null null The first-line effector mechanisms of immune defence, including inflammation and oxidative burst, contribute significantly to host-pathogen resistance. Whether these immune responses undergo age-related changes in birds remains unknown. Here, we tracked selected inflammatory parameters in 54 free-living great tits (Parus major) of known age, captured repeatedly over three consecutive years, with the aims to investigate long-term repeatability and age-dependent changes in cellu...
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Top fields of study
Endocrinology
Longevity
Ageing
Senescence
Diabetes mellitus
Medicine
Biology
Cell biology