Schizophrenia Bulletin
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#1Akihiro Takamiya (Allen Institute for Brain Science)H-Index: 11
#2Annemiek Dols (VU: VU University Amsterdam)H-Index: 22
Last. Eric van Exel (VU: VU University Amsterdam)H-Index: 17
view all 28 authors...
Psychotic major depression (PMD) is hypothesized to be a distinct clinical entity from nonpsychotic major depression (NPMD). However, neurobiological evidence supporting this notion is scarce. The aim of this study is to identify gray matter volume (GMV) differences between PMD and NPMD and their longitudinal change following electroconvulsive therapy (ECT). Structural magnetic resonance imaging (MRI) data from 8 independent sites in the Global ECT-MRI Research Collaboration (GEMRIC) database (n...
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#1Natalie Shoham (UCL: University College London)H-Index: 3
#2Joseph Hayes (UCL: University College London)H-Index: 32
Last. Gemma Lewis (UCL: University College London)H-Index: 8
view all 5 authors...
A cross-sectional association between visual impairment and psychosis exists, but longitudinal evidence from children and young people is limited. We investigated whether childhood visual acuity was associated with subsequent psychotic experiences. Our sample was 6686 individuals from the Avon Longitudinal Study of Parents and Children (ALSPAC). We investigated whether our primary exposures, best corrected visual acuity at ages 7 and 11, were associated with psychotic experiences at ages 17 and ...
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#1Evangelos Vassos (South London and Maudsley NHS Foundation Trust)H-Index: 32
#2Robin M. Murray ('KCL': King's College London)H-Index: 190
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#1Jamilla J Giles (UWA: University of Western Australia)
#2Ivan T. Ling (SCGH: Sir Charles Gairdner Hospital)H-Index: 4
Last. Flavie Waters (UWA: University of Western Australia)H-Index: 9
view all 9 authors...
Obstructive sleep apnea (OSA) is a highly prevalent condition in people living with schizophrenia or other psychotic disorder. Its treatment with continuous positive airway pressure therapy (CPAP) can dramatically improve daytime and physical health function. People with a psychotic disorder, however, are rarely diagnosed and treated and there are no large-scale studies showing evidence of successful treatment with CPAP. Using a retrospective case-control study approach (N = 554), we examined ad...
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#1Alejandro Szmulewicz (Harvard University)H-Index: 5
#2Brian T. Bateman (Brigham and Women's Hospital)H-Index: 65
Last. Krista F. Huybrechts (Brigham and Women's Hospital)H-Index: 53
view all 4 authors...
The US FDA issued a black-box warning against co-prescription of antipsychotic (AP) agents and opioids due to the risk of respiratory depression, but evidence on the comparative safety of sedating vs nonsedating APs is lacking. We classified APs as sedating (eg, quetiapine, olanzapine, and chlorpromazine) and nonsedating (eg, aripiprazole, haloperidol, and risperidone) based on their affinity to the histamine-1 neuroreceptor (Ki < or ≥20, respectively) and sought to compare the rate of overdose ...
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#1Michelle Worthington (Yale University)H-Index: 3
#2Jean Addington (Allen Institute for Brain Science)H-Index: 5
Last. William S. Stone (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 55
view all 14 authors...
The clinical high-risk period before a first episode of psychosis (CHR-P) has been widely studied with the goal of understanding the development of psychosis; however, less attention has been paid to the 75%-80% of CHR-P individuals who do not transition to psychosis. It is an open question whether multivariable models could be developed to predict remission outcomes at the same level of performance and generalizability as those that predict conversion to psychosis. Participants were drawn from ...
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#1Anna R. Docherty (UofU: University of Utah)H-Index: 22
#2Amanda V. Bakian (UofU: University of Utah)H-Index: 16
Last. Douglas GrayH-Index: 8
view all 11 authors...
Approximately 5% of individuals with schizophrenia die from suicide. However, suicide in psychosis is still poorly characterized, partly due to a lack of adequate population-based clinical or genetic data on suicide death. The Utah Suicide Genetics Research Study (USGRS) provides a large population-based cohort of suicide deaths with medical record and genome-wide data (N = 4380). Examination of this cohort identified medical and genetic risks associated with type of suicide death and investigat...
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#1Wolfgang Strube (University of Augsburg)H-Index: 15
#2Camelia Lucia Cimpianu (LMU: Ludwig Maximilian University of Munich)
Last. Alkomiet Hasan (University of Augsburg)H-Index: 43
view all 9 authors...
Background null Jumping-to-conclusions (JTC) is a prominent reasoning bias in schizophrenia (SCZ). While it has been linked to not only psychopathological abnormalities (delusions and impulsive decision-making) but also unstable belief formation, its origin remains unclear. We here directly test to which extend JTC is associated with delusional ideation, impulsive decision-making, and unstable belief formation. null Methods null In total, 45 SCZ patients were compared with matched samples of 45 ...
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