Journal of Diabetes Investigation
Papers 1687
1 page of 169 pages (1,687 results)
#1Kazuhisa Watanabe (Jichi Medical University)H-Index: 9
#2Ayumi Matsumoto (Jichi Medical University)H-Index: 11
Last. Sadahiko Iwamoto (Jichi Medical University)H-Index: 15
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AIMS/INTRODUCTION It was reported previously that N4bp2l1 expression increases in 3T3-L1 cells in a differentiation-dependent manner and N4bp2l1 knockdown suppresses adipocyte differentiation. However, the physiological function of N4BP2L1 in adipocytes remains unknown. This study aimed to elucidate the physiological mechanism of N4bp2l1 expression and the role of N4BP2L1 in the physiological function of adipocytes. MATERIALS AND METHODS Analysis of gene expression levels of N4bp2l1 in adipose t...
#1Takashi Wada (Kanazawa University)H-Index: 61
#2Kazumi Mori-Anai (Mitsubishi Tanabe Pharma)
Last. Meg Jardine (The George Institute for Global Health)H-Index: 43
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AIM The sodium-glucose cotransporter 2 inhibitor canagliflozin reduced kidney failure and cardiovascular events in the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial. We conducted a post-hoc analysis to evaluate the efficacy and safety of canagliflozin in a subgroup of participants in East and Southeast Asian (EA) countries who are at high risk of renal complications. METHODS Participants with an estimated glomerular filtration rate o...
#1Noriharu YagiH-Index: 2
#2Ichiro KomiyaH-Index: 28
Last. Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 72
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AIMS/INTRODUCTION Type 2 diabetes mellitus (T2DM) is caused by a relative imbalance between insulin secretion and sensitivity related to the body mass index (BMI). Seven categories of oral antidiabetic drugs (OADs) are available in Japan. It is important to assess the OAD utilization patterns based on patients' BMI levels. MATERIALS AND METHODS OAD prescribing patterns from 2002 to 2019 were analyzed using the data collected in the computerized diabetes care (CoDiC) database provided by the Japa...
#1Yoko Ueba (Kyoto University)H-Index: 1
#2Takaaki Murakami (Kyoto University)H-Index: 7
Last. Daisuke Yabe (Kyoto University)H-Index: 35
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AIMS/INTRODUCTION An efficient screening strategy for identification of cognitive dysfunction remains a clinical issue in the management of elderly adults with diabetes. A magnetic resonance imaging voxel-based specific regional analysis system for Alzheimer's disease (VSRAD) has been developed as an automated brain morphometry system that includes the hippocampus. We carried out a multicenter retrospective study to evaluate the utility of VSRAD for screening cognitive dysfunction in diabetes ou...
#1Mongkontida Umphonsathien (King Chulalongkorn Memorial Hospital)H-Index: 1
#2Peedaporn Rattanasian (King Chulalongkorn Memorial Hospital)
Last. Weerapan Khovidhunkit (King Chulalongkorn Memorial Hospital)H-Index: 1
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Aim null /Hypothesis: Very few studies assess the effectiveness of different protocols of intermittent very-low calorie diet (VLCD) in patients with diabetes. This study was designed to compare the effects of 2 days/week and 4 days/week of intermittent VLCD on glycemic control, diabetes remission, metabolic parameters, and quality of life (QoL) in patients with type 2 diabetes and obesity. null Methods null Participants with obesity and type 2 diabetes were recruited and randomly assigned to 3 g...
#1Yu HoribaH-Index: 1
#2Kaya IshizawaH-Index: 3
Last. Tetsuya BabazonoH-Index: 30
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AIMS/INTRODUCTION This study aimed to determine the effect of depression on the progression to end-stage renal disease (ESRD) and pre-ESRD death in patients with advanced diabetic nephropathy. MATERIALS AND METHODS This single-center prospective cohort study enrolled Japanese patients with type 2 diabetes and advanced diabetic nephropathy. The total Patient Health Questionnaire-9 score was used to evaluate depression at baseline and classified patients into: no, mild and severe depression groups...
#1Shuhei Nakanishi (Kawasaki Medical School)H-Index: 9
#2Masashi Shimoda (Kawasaki Medical School)H-Index: 14
Last. Hideaki Kaneto (Kawasaki Medical School)H-Index: 66
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This study examined the association between Grit Scales and adherence to a schedule of regular hospital visits in Japanese type 2 diabetes patients. Patients with type 2 diabetes who visited the outpatient clinic as new patients comprised the study's participants. Self-administered Short Grit Scale (Grit-S) data were obtained from 122 patients at the first consultation and were then observed for one year. As the results, 21 participants failed to attend the hospital. In a logistic regression ana...
#1Tatsuhiko Urakami (Nihon University)H-Index: 22
#2Kei Yoshida (Nihon University)H-Index: 3
Last. Ichiro Morioka (Nihon University)H-Index: 21
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AIMS /Introduction We examined the impact of scanning frequency with flash glucose monitoring (FGM) on glycemic control in children and adolescents with type 1 diabetes. MATERIALS AND METHODS The study included 85 patients, aged 14.0±0.5 years, with type 1 diabetes. The median time in the target glucose range (TIR) and glycosylated hemoglobin (HbA1c) values were 50.0±1.4% and 7.5±0.1%, respectively. RESULTS The median scanning frequency using FGM was 12.0±0.4 times/ day. Scanning frequency showe...
Last. Li Hong (CQMU: Chongqing Medical University)
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AIMS/INTRODUCTION Emerging evidences have indicated that lncRNAs play important roles in the development and progression of Diabetic retinopathy (DR). It is reported that UCA1 was highly expressed in diabetic lymphoendothelial cells and influences glucose metabolism in rats with DR. The aim of the present study was to explore the role of UCA1 in the mechanism of DR. METHODS Gene expression analyses in fibrovascular membranes excised from patients with DR using public microarray datasets (GSE6043...
#1Yu Jin (Nanjing Medical University)
#2Weimin Wang (NU: Nanjing University)H-Index: 3
Last. Yan Bi (Nanjing Medical University)H-Index: 19
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AIM To investigate the diagnostic utility of corneal confocal microscopy (CCM) for small fiber neuropathy in type 2 diabetes. MATERIALS AND METHODS There were altogether 186 participants with type 2 diabetes enrolled in this cross-sectional research. We defined pure small fiber neuropathy and mixed fiber neuropathy using clinical examination, electromyography, and quantitative sensory testing. Demographics and clinical data, CCM parameters, and other neuropathy measures were compared among group...
Top fields of study
Type 2 diabetes
Diabetes mellitus