Laura Mercer-Rosa
University of Pennsylvania
Interquartile rangeInternal medicineSurgeryCardiologyRetrospective cohort studyPediatricsCardiac magnetic resonance imagingTetralogy of FallotCardiac surgeryVentricleDiseaseHeart diseasePulmonary hypertensionPulmonary insufficiencyPopulationVentricular functionPerioperativeDiastoleMedicineCohortEjection fraction
101Publications
17H-index
920Citations
Publications 104
Newest
#1Jonathan B EdelsonH-Index: 2
#2Monique M. GardnerH-Index: 4
Last. Kimberly Y. LinH-Index: 14
view all 15 authors...
Introduction: Children with single ventricle (SV) congenital heart disease have high morbidity, mortality and resource utilization when admitted to the hospital but few data exist on emergency depa...
#2W. Wong (UPenn: University of Pennsylvania)H-Index: 2
#8Kimberly Y. Lin (UPenn: University of Pennsylvania)H-Index: 14
The importance of preoperative cardiac function in pediatric lung transplantation is unknown. We hypothesized that worse preoperative right ventricular (RV) systolic and worse left ventricular (LV) diastolic function would be associated with a higher risk of primary graft dysfunction grade 3 (PGD 3) between 48 and 72 hours. We performed a single center, retrospective pilot study of children (<18 years) who had echocardiograms <1 year prior to lung transplantation between 2006 and 2019. Conventio...
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#1Jonathan B Edelson (UPenn: University of Pennsylvania)H-Index: 2
#5Chitra Ravishankar (UPenn: University of Pennsylvania)H-Index: 15
Last. Kimberly Y. Lin (UPenn: University of Pennsylvania)H-Index: 14
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Background Children with congenital heart disease (CHD) are known to consume a disproportionate share of resources, yet there are limited data concerning trends in resource use and mortality among ...
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#6Chitra Ravishankar (Children's Hospital of Philadelphia)H-Index: 15
Neurodevelopmental sequelae are prevalent among patients with congenital heart defects (CHD). In a study of infants and children with repaired tetralogy of Fallot (TOF), we sought to identify those at risk for abnormal neurodevelopment and to test associations between socioeconomic and medical factors with neurodevelopment deficits. Single-center retrospective observational study of patients with repaired TOF that were evaluated at the institution’s Cardiac Kids Developmental Follow-up Program (...
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#1Ranjini Srinivasan (NYU: New York University)
#2Jennifer Faerber (Children's Hospital of Philadelphia)H-Index: 16
Last. Laura Mercer-Rosa (Children's Hospital of Philadelphia)H-Index: 17
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#9Maryam Y. Naim (Children's Hospital of Philadelphia)H-Index: 2
Introduction: Tetralogy of Fallot (TOF) repair is associated with excellent operative survival. However, a subset of patients experiences post-operative complications, which can significantly alter the early and late post-operative course. We utilized a machine learning approach to identify risk factors for post-operative complications after TOF repair. Methods: We conducted a single-center prospective cohort study of children <2 years of age with TOF undergoing surgical repair. The outcome was ...
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#2Laura Mercer-RosaH-Index: 17
Last. Victoria L. VetterH-Index: 45
view all 5 authors...
Introduction: Electrical-mechanical interactions contribute to arrhythmias, sudden cardiac death, and right ventricular remodeling in repaired tetralogy of Fallot (TOF). Hypothesis: There are signi...
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#1Catherine M. Avitabile (UPenn: University of Pennsylvania)H-Index: 11
#2Yan Wang (Children's Hospital of Philadelphia)H-Index: 8
Last. Laura Mercer-Rosa (Children's Hospital of Philadelphia)H-Index: 17
view all 12 authors...
RATIONALE Brain natriuretic peptide correlates with pulmonary hypertension by echocardiogram in congenital diaphragmatic hernia, however its association with right ventricular function and mortality is unknown. OBJECTIVE To characterize the relationships between echocardiogram-derived right ventricular strain, brain natriuretic peptide, and mortality in diaphragmatic hernia. METHODS We performed a single-center, retrospective cohort study of infants with diaphragmatic hernia and at least one bra...
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#1Joyce C. Chang (UPenn: University of Pennsylvania)H-Index: 6
#2Yan Wang (Children's Hospital of Philadelphia)H-Index: 8
Last. Laura Mercer-Rosa (UPenn: University of Pennsylvania)H-Index: 17
view all 10 authors...
BACKGROUND Strain analysis with speckle-tracking echocardiography shows promise as a screening tool for silent myocardial dysfunction in pediatric-onset systemic lupus erythematosus (pSLE). We compared left ventricular (LV) systolic deformation (measured by strain) in children and adolescents with pSLE to controls, and assessed the relationship between strain, disease activity, and other noninvasive measures of cardiovascular health. METHODS Twenty pSLE subjects ages 9-21 underwent comprehensive...
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#1Matthew J. Campbell (Children's Hospital of Philadelphia)H-Index: 4
#2Michael D. Quartermain (Children's Hospital of Philadelphia)H-Index: 14
Last. David J. Goldberg (Children's Hospital of Philadelphia)H-Index: 27
view all 10 authors...
BACKGROUND While numerous indices have been developed in an attempt to quantify ventricular function in patients with single ventricle heart disease after Fontan, there are little data on how these parameters change over time. METHODS A retrospective observational study was performed of individuals who underwent Fontan operation at Children's Hospital of Philadelphia (CHOP) in 2006 and 2007. Measurements of fractional area change (FAC), tricuspid annular planar systolic excursion (TAPSE), myocar...
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