Kazuhiro Tateda
Toho University
Internal medicineChemistryImmunologyLegionella pneumophilaKlebsiella pneumoniaePseudomonas aeruginosaPneumoniaSepsisVancomycinStaphylococcus aureusImipenemStreptococcus pneumoniaeLegionella PneumoniaAntibacterial agentAntimicrobialAntibioticsBacteriaMedicineBiologyMicrobiologyAntibiotic resistance
298Publications
35H-index
4,156Citations
Publications 300
Newest
Background null Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is generally diagnosed by reverse transcription (RT)-PCR or serological assays. The SARS-CoV-2 viral load decreases a few days after symptom onset. Thus, the RT-PCR sensitivity peaks at three days after symptom onset (approximately 80%). We evaluated the performance of the ARCHITECT® SARS-CoV-2 IgG assay (henceforth termed IgG assay; Abbott Laboratories, Lake County, IL, U...
2 CitationsSource
#1Yukinobu OkajimaH-Index: 3
#2Takashi SuzukiH-Index: 21
Last. Yuichi HoriH-Index: 25
view all 10 authors...
Lacrimal canaliculitis is a rare infection of the lacrimal canaliculi with canalicular concretions formed by aggregation of organisms. Metagenomic shotgun sequencing analysis using next-generation sequencing has been used to detect pathogens directly from clinical samples. Using this technology, we report cases of successful pathogen detection of canalicular concretions in lacrimal canaliculitis cases. We investigated patients with primary lacrimal canaliculitis examined in the eye clinics of fo...
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#1Takashi Ueda (Hyogo College of Medicine)H-Index: 8
#2Yoshio Takesue (Hyogo College of Medicine)H-Index: 21
Last. Hideki Kawamura (Kadai: Kagoshima University)H-Index: 8
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Inappropriate antimicrobial therapy for surgical site infections (SSIs) can lead to poor outcomes and an increased risk of antibiotic resistance. A nationwide survey was conducted in Japan from 2018 to 2019 to investigate the antimicrobial susceptibility of pathogens isolated from SSIs. The data were compared with those obtained in 2010 and 2014-2015 surveillance studies. Although the rate of detection of extended-spectrum β-lactamase producing strains of Escherichia coli was increased from 9.5%...
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#1Kageto Yamada (Toho University)H-Index: 5
#2Masakazu Sasaki (Toho University)H-Index: 2
Last. Kazuhiro Tateda (Toho University)H-Index: 35
view all 7 authors...
Abstract null null Carbapenemase-producing Enterobacterales null (CPE) have become a global health concern. Current molecular detection methods require special equipment and reagents. Thus, there is an urgent need for a highly sensitive, specific, and simple method for phenotypic detection of CPE in null clinical microbiology null null null null laboratories. A simplified carbapenem inactivation method (sCIM) was recently reported. However, its utility for CPE detection has not been sufficiently...
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#1Mami Hanao (Toho University)
#2Kotaro Aoki (Toho University)H-Index: 11
Last. Kazuhiro Tateda (Toho University)H-Index: 35
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Objectives To investigate the spread of ceftriaxone-resistant Neisseria gonorrhoeae lineages similar to strains H041 (2009) and FC428 (2015), we characterized 55 strains collected in 2013 from hospitals across Japan. Methods Susceptibility testing and whole-genome sequencing. Results Susceptibility rates were 58% for cefixime and 98% for ceftriaxone. The 55 strains were whole-genome sequenced and classified into nine MLST-STs. MLST-ST1901 was the most prevalent (n = 19) followed by MLST-ST7363 (...
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#1Tetsuji Aoyagi (Tohoku University)H-Index: 17
#2Yusuke Takei (Tohoku University)H-Index: 3
Last. M. Kaku (Tohoku Pharmaceutical University)
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#1Takashi Sakai (Toho University)H-Index: 6
#2Yoko Azuma (Toho University)H-Index: 3
Last. Akira Iyoda (Toho University)H-Index: 31
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A 65-year-old man with coronavirus disease 2019 (COVID-19) was admitted to our hospital. Computed tomography detected bilateral pneumonia with a lung nodule suspicious for lung cancer. Lobectomy was performed 3 months after the treatment for COVID-19 without any complications. The surgical specimen revealed fibrosis below the pleura with a small collection of lymphocytes and intravascular hemorrhagic thrombosis, and no residual RNA was detected. This is the first report describing a surgical spe...
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#1Hiroe Konishi McKee (Toho University)
#2Chiaki Kajiwara (Toho University)H-Index: 10
Last. Kazuhiro Tateda (Toho University)H-Index: 35
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Introduction.Clostridioides difficile infection (CDI) causes toxin-mediated enteropathy, such as antibiotic-associated diarrhoea and pseudomembranous colitis. Rho-glucosylating toxin A (TcdA) and toxin B (TcdB) have been clearly implicated in pathogenesis, whereas the virulence of binary toxin (CDT) is still debated.Hypothesis statement. We hypothesized that CDT is involved in the host immune response and plays a pivotal role in establishing virulence by modulating pro-inflammatory cytokine prod...
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#1Kotaro Aoki (Toho University)H-Index: 11
#2Tatsuya Nagasawa (Toho University)H-Index: 2
Last. Kazuhiro Tateda (Toho University)H-Index: 35
view all 10 authors...
Abstract Background Expansion of the testing capacity for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important issue to mitigate the pandemic of coronavirus disease-2019 (COVID-19) caused by this virus. Recently, a sensitive quantitative antigen test (SQT), Lumipulse® SARS-CoV-2 Ag, was developed. It is a fully automated chemiluminescent enzyme immunoassay system for SARS-CoV-2. Methods In this study, the analytical performance of SQT was examined using clinical specimens...
15 CitationsSource
#1T. Kasai (Toho University)
#2Y. Fukui (Toho University)
Last. Kazuhiro Tateda (Toho University)H-Index: 35
view all 5 authors...
AIMS Otitis externa (OE), one of the most common ear diseases in dogs, is caused by bacterial pathogens such as Staphylococcus sp. To understand the network of microbial communities in the canine ear canal affected with OE, we performed a cross-sectional study using next-generation sequencing. METHODS AND RESULTS Ear swab samples were collected from 23 OE-affected and 10 healthy control dogs, and the 16S rRNA gene sequenced using Illumina MiSeq. The otic microbiota in the OE-affected dogs showed...
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