Heinz Reichmann
Dresden University of Technology
PsychiatryInternal medicineEndocrinologyDopaminergicPathologyPsychologyCardiologyNeurologyNeurosciencePhysical therapyPediatricsDiseaseParkinson's diseaseLevodopaAnesthesiaDopamineStrokeMedicineBiologyPhysical medicine and rehabilitation
Publications 496
#1Sotirios Grigoriou (Lund University)H-Index: 2
#2Pablo Martinez-Martin (ISCIII: Carlos III Health Institute)H-Index: 60
Last. Heinz Reichmann (TUD: Dresden University of Technology)H-Index: 59
view all 9 authors...
Background null Non-motor symptoms (NMS) are integral to Parkinson's Disease (PD) and management remains a challenge. Safinamide is a novel molecule in relation to addressing NMS due to its multifocal mechanism of action with both dopaminergic and non-dopaminergic properties. null Objective null To investigate the efficacy of safinamide on NMS and its burden in PD patients with motor fluctuations after 6 months of treatment. null Methods null This observational, multicenter, open-label, pilot st...
#1Annahita Sedghi (TUD: Dresden University of Technology)H-Index: 5
#2Timo Siepmann (TUD: Dresden University of Technology)H-Index: 17
Last. Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
view all 7 authors...
We aimed to assess how evidence-based stroke care changed over the two waves of the COVID-19 pandemic. We analyzed acute stroke patients admitted to a tertiary care hospital in Germany during the first (2 March 2020-9 June 2020) and second (23 September 2020-31 December 2020, 100 days each) infection waves. Stroke care performance indicators were compared among waves. A 25.2% decline of acute stroke admissions was noted during the second (n = 249) compared with the first (n = 333) wave of the pa...
#1Christian Hartmann (TUD: Dresden University of Technology)H-Index: 1
#2Simon Winzer (TUD: Dresden University of Technology)H-Index: 5
Last. Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
view all 13 authors...
BACKGROUND AND PURPOSE Hypothermia may be neuroprotective in acute ischemic stroke. Patients with anterior circulation large vessel occlusion (acLVO) are frequently hypothermic after endovascular therapy (EVT). We sought to determine whether this inadvertent hypothermia is associated with improved outcome. METHODS We extracted data of consecutive patients (01/2016-05/2019) who received EVT for acLVO from our prospective EVT register of all patients screened for EVT at our tertiary stroke center....
1 CitationsSource
#1Nicole König (University of Regensburg)H-Index: 1
#2Henning Stetefeld (University of Cologne)H-Index: 10
Last. Bernhard Neumann (University of Regensburg)H-Index: 7
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Myasthenic crisis (MC) is a life-threatening condition for patients with myasthenia gravis (MG). Muscle-specific kinase-antibodies (MuSK-ABs) are detected in ~ 6% of MG, but data on outcome of MuSK-MCs are still lacking. We made a subgroup analysis of patients who presented with MC with either acetylcholine-receptor-antibody positive MG (AchR-MG) or MuSK-MG between 2006 and 2015 in a retrospective German multicenter study. We identified 19 MuSK-AB associated MCs in 15 patients and 161 MCs in 144...
1 CitationsSource
#1Simon Winzer (TUD: Dresden University of Technology)H-Index: 5
#2Henning RickmannH-Index: 3
Last. Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
view all 19 authors...
Purpose We sought to determine the diagnostic agreement between the revised ultrasonography approach by the German Society of Ultrasound in Medicine (DEGUM) and the established Society of Radiologists in Ultrasound (SRU) consensus criteria for the grading of carotid artery disease. Materials and methods Post-hoc analysis of a prospective multicenter study, in which patients underwent ultrasonography and digital subtraction angiography (DSA) of carotid arteries for validation of the DEGUM approac...
#1Robert D. Nass (University Hospital Bonn)H-Index: 12
#2Katja Akgün (TUD: Dresden University of Technology)H-Index: 10
Last. Rainer Surges (University Hospital Bonn)H-Index: 34
view all 7 authors...
Introduction: Our goal was to investigate whether biomarkers of cerebral damage are found in autoimmune mediated epilepsy (AIE) and whether these can differentiate AIE from other seizure disorders. Methods: We retrospectively searched our CSF database for patients with definite AIE, hippocampal sclerosis due to other causes (HS), idiopathic generalized epilepsy (IGE) and psychogenic, non-epileptic seizures (PNES). We measured serum and CSF Tau, neurofilament 1 (NFL), glial fibrillary acid protei...
#1Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
#2Stanislava Jakubicek (Masaryk University)H-Index: 3
Last. Andrei V. Alexandrov (UTHSC: University of Tennessee Health Science Center)H-Index: 27
view all 16 authors...
Background: We hypothesized that auto-titrating bilevel positive airway pressure (auto-BPAP) favorably affects short-term clinical outcomes in hyperacute ischemic stroke. Methods: In a multicenter, randomized, controlled trial patients with large vessel steno-occlusive stroke and clinically suspected sleep apnea were allocated to auto-BPAP or standard stroke care alone. Auto-BPAP was initiated within 24 hours from stroke onset and performed over 48 hours during diurnal and nocturnal sleep. Sleep...
#1Haidar Moustafa (TUD: Dresden University of Technology)H-Index: 4
#2Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
Last. Jessica Barlinn (TUD: Dresden University of Technology)H-Index: 7
view all 13 authors...
IntroductionRecent exploratory analysis suggested comparable outcomes among stroke patients undergoing endovascular therapy (EVT) for anterior circulation large vessel occlusion, whether selected v...
6 CitationsSource
#1Kai F. Loewenbrück (TUD: Dresden University of Technology)H-Index: 4
#2Robin Werner (TUD: Dresden University of Technology)
Last. Andreas Hermann (University of Rostock)H-Index: 8
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OBJECTIVE To investigate diagnostic accuracy of a nerve ultrasound (US) protocol that is individualized to a patient's clinical deficits for the differentiation of amyotrophic lateral sclerosis with predominant lower motoneuron disease (ALS/LMND) and multifocal motor neuropathy (MMN). METHODS Single-center, prospective, examiner-blinded, diagnostic study in two cohorts. Cohort I (model development): Convenience sample of subjects with ALS/LMND or MMN according to revised El-Escorial or EFNS guid...
1 CitationsSource
#2Qi ShangH-Index: 1
Last. Francisco Pan-Montojo (LMU: Ludwig Maximilian University of Munich)H-Index: 9
view all 16 authors...
Parkinson's disease (PD) is known to involve the peripheral nervous system (PNS) and the enteric nervous system (ENS). Functional changes in PNS and ENS appear early in the course of the disease and are responsible for some of the non-motor symptoms observed in PD patients like constipation, that can precede the appearance of motor symptoms by years. Here we analyzed the effect of the pesticide rotenone, a mitochondrial Complex I inhibitor, on the function and neuronal composition of the ENS by ...