Barry A. Borlaug
Mayo Clinic
Internal medicineCardiac outputPulmonary wedge pressureCardiologyIntensive care medicineHemodynamicsHeart failure with preserved ejection fractionCardiac catheterizationHeart rateHeart failureAtrial fibrillationPulmonary hypertensionPulmonary arteryPopulationIn patientDiastoleVascular resistanceMedicineEjection fractionStroke volumeBlood pressure
463Publications
76H-index
19.3kCitations
Publications 460
Newest
#1Hidemi Sorimachi (Mayo Clinic)H-Index: 2
#2Kazunori Omote (Mayo Clinic)H-Index: 1
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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Heart failure with preserved ejection fraction (HFpEF) accounts for more than one-half of patients with heart failure. Effective treatment of HFpEF has not been established, largely because of the complexities and heterogeneity in the phenotypes of HFpEF. Categorizing patients based on clinical and pathophysiologic phenotype may provide more targeted and efficacious therapies. Despite this clinical need, there is no consensus on how to categorize patients with HFpEF into phenogroups. Possible me...
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#1Vidhu Anand (Mayo Clinic)H-Index: 14
#2David S Bradley (Mayo Clinic)H-Index: 8
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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#1Michael I. Brener (CUMC: Columbia University Medical Center)H-Index: 3
#2Nadira Hamid (CUMC: Columbia University Medical Center)H-Index: 8
Last. Daniel Burkhoff (CUMC: Columbia University Medical Center)H-Index: 16
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#1Pieter MartensH-Index: 17
#2Lieven HerbotsH-Index: 25
Last. Jan Verwerft (University of Hasselt)H-Index: 1
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Little data is available about the pathophysiological mechanisms of unexplained dyspnea and their clinical meaning. Consecutive patients with unexplained dyspnea underwent prospective standardized cardiopulmonary exercise testing with echocardiography (CPETecho). Patients were grouped as having normal exercise capacity (peak VO2 > 80% with respiratory exchange [RER] > 1.05), reduced exercise capacity (peak VO2 ≤ 80% with RER > 1.05), or a submaximal exercise test (RER ≤ 1.05). From 307 patients,...
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#1Christine Jellis (Cleveland Clinic)H-Index: 10
#2Margaret M. Park (Cleveland Clinic)H-Index: 13
Last. Kim Jiwon (Cornell University)
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AIMS There is a wide spectrum of diseases associated with pulmonary hypertension, pulmonary vascular remodelling, and right ventricular dysfunction. The NIH-sponsored PVDOMICS network seeks to perform comprehensive clinical phenotyping and endophenotyping across these disorders to further evaluate and define pulmonary vascular disease. METHODS AND RESULTS Echocardiography represents the primary non-invasive method to phenotype cardiac anatomy, function, and haemodynamics in these complex patient...
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#1Vinayak Kumar (Mayo Clinic)H-Index: 3
#2Armando Manduca (Mayo Clinic)H-Index: 59
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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BACKGROUND Myocardial volume is assumed to be constant over the cardiac cycle in the echocardiographic models used by professional guidelines, despite evidence that suggests otherwise. The aim of this paper is to use literature-derived myocardial strain values from healthy patients to determine if myocardial volume changes during the cardiac cycle. METHODS A systematic review for studies with longitudinal, radial, and circumferential strain from echocardiography in healthy volunteers ultimately ...
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#1Abhinav Sharma (MUHC: McGill University Health Centre)H-Index: 23
#2Stephen J. Greene (Duke University)H-Index: 38
Last. G. Michael Felker (Duke University)H-Index: 94
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AIMS Associations between growth differentiation factor-15 (GDF-15), cardiovascular outcomes, and exercise capacity among patients with a recent hospitalization for heart failure (HHF) and heart failure with reduced ejection fraction (HFrEF) are unknown. We utilized data from the 'Functional Impact of GLP-1 for Heart Failure Treatment' (FIGHT) study to address these knowledge gaps. METHODS AND RESULTS FIGHT was a randomized clinical trial testing the effect of liraglutide (vs. placebo) among 300...
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#1Hidemi Sorimachi (Mayo Clinic)H-Index: 2
#2Daniel BurkhoffH-Index: 75
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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AIMS Circulating blood volume (BV) is functionally divided between the unstressed volume, which fills the vascular space, and stressed blood volume (SBV), which generates vascular wall tension and intravascular pressure. With decreases in venous capacitance, blood functionally shifts to the SBV, increasing central venous pressure (CVP) and pulmonary venous pressures. Obesity is associated with both elevated CVP and heart failure with preserved ejection fraction (HFpEF). To explore the mechanisms...
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#1Masaru Obokata (Mayo Clinic)H-Index: 22
#2Yogesh N.V. Reddy (Mayo Clinic)H-Index: 26
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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ABSTRACT Background A warmup period of “priming” exercise has been shown to improve peripheral oxygen transport in older adults. We sought to determine the acute effects of priming exercise on central hemodynamics at rest and during a repeat exercise in heart failure with preserved ejection fraction (HFpEF). Methods and Results This is a post-hoc analysis from three studies. Subjects with HFpEF (n=42) underwent cardiac catheterization with simultaneous expired gas analysis at rest and during exe...
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