Abbas Agaimy
University of Erlangen-Nuremberg
CancerRadiologySurgeryPathologyOncologySMARCB1ImmunohistochemistryGiSTBiopsyCarcinomaSarcomaSalivary glandMetastasisMalignancyDifferential diagnosisPDGFRACancer researchMedicineBiologyGastroenterology
Publications 513
#1Alena SkálováH-Index: 32
#2Ilmo LeivoH-Index: 42
Last. Alfio FerlitoH-Index: 64
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High-grade transformation (HGT) or dedifferentiation has been described in a variety of salivary gland carcinomas, including acinic cell carcinoma, secretory carcinoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, polymorphous adenocarcinoma, low-grade mucoepidermoid carcinoma, and hyalinizing clear cell carcinoma. High-grade (HG) transformed tumors are composed of a conventional low-grade component characterized by specific microscopic and immunohistochemical features for the g...
#1Michael Michal (Charles University in Prague)H-Index: 12
#2Brian P. Rubin (Cleveland Clinic)H-Index: 61
Last. Michal Michal (Charles University in Prague)H-Index: 52
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The knowledge of clinical features and, particularly, histopathological spectrum of EWSR1-PATZ1-rearranged spindle and round cell sarcomas (EPS) remains limited. For this reason, we report the largest clinicopathological study of EPS to date. Nine cases were collected, consisting of four males and five females ranging in age from 10 to 81 years (average: 49 years). Five tumors occurred in abdominal wall soft tissues, three in the thorax, and one in the back of the neck. Tumor sizes ranged from 2...
2 CitationsSource
#1Abbas Agaimy (FAU: University of Erlangen-Nuremberg)H-Index: 45
#2Michael Michal (Charles University in Prague)H-Index: 12
Last. Kemal Kosemehmetoglu (Hacettepe University)H-Index: 12
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Giant cell tumors of soft tissue (GCT-ST) are rare low-grade neoplasms that were at one time thought to represent the soft tissue counterparts of GCT of bone (GCT-B) but are now known to lack the H3F3 mutations characteristic of osseous GCT. We present six distinctive giant cell-rich soft tissue neoplasms that expressed keratins and carried a recurrent HMGA2-NCOR2 gene fusion. Patients were five females and one male aged 14-60 years (median, 29). All presented with superficial (subcutaneous) mas...
#1Kiril Trpkov (U of C: University of Calgary)H-Index: 34
#2Sean R. Williamson (Cleveland Clinic)H-Index: 28
Last. Ondrej Hes (Charles University in Prague)H-Index: 36
view all 42 authors...
#1Konstantinos Mantsopoulos (FAU: University of Erlangen-Nuremberg)H-Index: 16
#2Ann-Kristin Iro (FAU: University of Erlangen-Nuremberg)H-Index: 1
Last. Heinrich Iro (FAU: University of Erlangen-Nuremberg)H-Index: 38
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Abstract Objectives The aim of this study was to compare several surgical modalities with respect to the incidence of positive margins and focal capsular exposure of parotideal pleomorphic adenoma. Methods The clinical records and histopathological findings of all patients who underwent parotidectomy for pleomorphic adenoma between 2006 and 2020 were evaluated retrospectively. Results 845 cases made up our study sample. The lesion was removed by means of extracapsular dissection in 577 cases (68...
#1Manuel Ruh (FAU: University of Erlangen-Nuremberg)H-Index: 1
#2Marc P. Stemmler (FAU: University of Erlangen-Nuremberg)H-Index: 22
Last. Simone Brabletz (FAU: University of Erlangen-Nuremberg)H-Index: 14
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Osteosarcoma is an often-fatal mesenchyme-derived malignancy in children and young adults. Overexpression of EMT-transcription factors (EMT-TFs) has been associated with poor clinical outcome. Here, we demonstrated that the EMT-TF ZEB1 is able to block osteoblastic differentiation in normal bone development as well as in osteosarcoma cells. Consequently, overexpression of ZEB1 in osteosarcoma characterizes poorly differentiated, highly metastatic subgroups and its depletion induces differentiati...
#1Kiril Trpkov (U of C: University of Calgary)H-Index: 34
#2Ondrej Hes (Charles University in Prague)H-Index: 36
Last. Anthony J. Gill (Kolling Institute of Medical Research)H-Index: 58
view all 42 authors...
The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide an update on existing entities, including diagnostic criteria, molecular correlates, and updated nomenclature. Key prognostic features for clear cell renal cell carcinoma (RCC) remain WHO/ISUP grade, AJCC/pTNM stage, coagulative necrosis, and rhabdoid and sarcomatoid differentiation. Accrual of subclonal genetic alterations in c...
#1Abbas Agaimy (FAU: University of Erlangen-Nuremberg)H-Index: 45
#2Abbas AgaimyH-Index: 45
Last. Michael ViethH-Index: 72
view all 25 authors...
1 CitationsSource
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