Hélène Arnould
University of Paris
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#1Hélène Arnould (University of Paris)
#2Vincent Baudouin (University of Paris)
Last. Marjorie Alvarez (University of Paris)
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Corruption of cellular prion protein (PrPC) function(s) at the plasma membrane of neurons is at the root of prion diseases, such as Creutzfeldt-Jakob disease and its variant in humans, and Bovine Spongiform Encephalopathies, better known as mad cow disease, in cattle. The roles exerted by PrPC, however, remain poorly elucidated. With the perspective to grasp the molecular pathways of neurodegeneration occurring in prion diseases, and to identify therapeutic targets, achieving a better understand...
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