Qing Chen
Linear rangeDetection limitTransduction (genetics)AptamerOligonucleotideChemistryConjugateCombinatorial chemistryNucleic acidNanoclustersSalmonella entericaMagnetic separationExonuclease IIIChromatographyDNAFluorescence
1Publications
1H-index
0Citations
Publications 4
Newest
#1Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
#2Jiaxin Zhang (NEAU: Northeast Agricultural University)
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
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Symbiotic gut microbiota in early life plays a vital role in human health, and changes in its communication and function are associated with various complex disorders. In this study, we analyzed the gut flora communication of 6 infants at 4 months of age and determined the disturbances related to antibiotic treatment. By the culturomics and Single Molecule Real-time sequencing methods, a total of 6234 strains were divided into 16 genera and 45 species. The alpha diversity of culturable microorga...
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#1Sihan ChenH-Index: 5
Last. Yujun JiangH-Index: 8
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Salmonella typhimurium (S. typhimurium) is a foodborne pathogen that has caused numerous outbreaks worldwide, necessitating the development of on-site strategy to prevent early contamination. Here, we set up an enzyme-free strategy for aptamer-catalyzed hairpin assembly in which salt-induced aggregation of unmodified gold nanoparticles (AuNPs) served as a colorimetric signal output, allowing on-site detection of S. typhimurium in milk. The aptamer-functionalized magnetic beads were used as a veh...
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#1Xinyan Yang (NEAU: Northeast Agricultural University)H-Index: 5
#2Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
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Abstract null null A novel fluorescent platform of DNA-stabilized silver nanoclusters (DNA-AgNCs) has been developed based on exonuclease III (Exo III) amplification-assisted for simple and sensitive detection of Salmonella Typhimurium (S. Typhimurium). The platform was designed by using magnetic beads, aptamer, its complementary DNA, hairpin probe (HP), Exo III, AgNO3, and NaBH4. The functionalized HP contained a cytosine-rich oligonucleotide loop (C-rich loop), which served as an effective tem...
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#1Pingping GaoH-Index: 1
#2Lihan WangH-Index: 2
Last. Yujun JiangH-Index: 8
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In this paper, a novel and ultrasensitive lateral flow assay (LFA) based on aptamer–magnetic separation, and multifold Au nanoparticles (AuNPs) was developed for visual detecting Salmonella enterica ser. Typhimurium (S. Typhimurium). The method realized magnetic enrichment and signal transduction via magnetic separation and achieved signal amplification through hybridizing AuNPs–capture probes and AuNPs–amplification probes to form multifold AuNPs. Two different thiolated single-strand DNA (ssDN...
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