Riccardo Sergi
Sapienza University of Rome
Materials scienceChitosanMechanical strengthPhoto crosslinkingCompressive strengthChemical engineeringTissue engineeringPorosityFreeze-dryingScaffold
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#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Riccardo Sergi (Sapienza University of Rome)
Last. Iolanda Francolini (Sapienza University of Rome)H-Index: 24
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Abstract In this study, a new scaffold fabrication method based on the combination of a series of stabilization processes was set up to obtain chitosan scaffolds with improved mechanical properties for regeneration of load-bearing tissues. Specifically, thermally induced phase separation (TIPS) of chitosan solutions was used to obtain an open structure which was then stabilized by freeze-gelation and photo cross-linking. Freeze-gelation combined with freeze-drying permitted to obtain a porous st...
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