Shenghou Wang
Shenyang Normal University
FermentationBiohydrogenChemistryHydrogen productionRyhBFormateGlycerolBiosynthesisBiochemistryMetabolism
Publications 2
#1Wan-Ying Chu (ZSTU: Zhejiang Sci-Tech University)
#2Ke Jiang (ZSTU: Zhejiang Sci-Tech University)
Last. Shenghou Wang (SYNU: Shenyang Normal University)
view all 11 authors...
BACKGROUND Biogenic 2,3-butanediol (2,3-BDO) is a high-value-added compound that can be used as a liquid fuel and a platform chemical. Bioproduction of 2,3-BDO is an environmentally friendly choice. METHOD AND RESULTS Three recombinant derivatives of the novel Klebsiella sp. isolate FSoil 024 (WT) were constructed via different strategies including deletion of lactate dehydrogenase by λ-Red homologous recombination technology, overexpression of the small-noncoding RNA RyhB and a combination of b...
#1Wan-Ying Chu (ZSTU: Zhejiang Sci-Tech University)
#2Yu-Dong Xu (ZSTU: Zhejiang Sci-Tech University)
Last. Hongxin Zhao (ZSTU: Zhejiang Sci-Tech University)H-Index: 12
view all 8 authors...
Abstract Biotechnological hydrogen production is considered as an environmentally sustainable alternative to petrochemical sources or electrolysis. Here, disruption of lactate dehydrogenase (LDH) and metabolic regulation via the small RNA RyhB were adopted to improve hydrogen production in the novel Klebsiella sp. strain FSoil 024. The hydrogen production of FSoil 024-L (Δldh) and FSoil 024-L/R (Δldh/RyhB) from glucose in a 5-L fermenter respectively increased by 40 and 50% compared to the wild ...
1 CitationsSource