María Ángeles López-García
Carlos III Health Institute
Internal medicineOncologyAntibodyPrognostic variableImmunohistochemistryBiopsyAtezolizumabImmunotherapyMetastasisLymphTriple-negative breast cancerSentinel lymph nodeCompanion diagnosticLymph nodePD-L1Patient follow upNomogramBreast cancerGeneral surgeryMedicine
4Publications
2H-index
1Citations
Publications 4
Newest
#1Begoña VieitesH-Index: 9
Last. Vicente PegH-Index: 28
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#1Vicente Peg (ISCIII: Carlos III Health Institute)H-Index: 1
#2María Ángeles López-García (ISCIII: Carlos III Health Institute)H-Index: 2
Last. Federico RojoH-Index: 33
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Triple-negative breast cancer (TNBC) is more aggressive than other breast cancer subtypes. TNBC is characterized by increased expression of Programmed Death-ligand 1 (PD-L1), a signal used by many tumors to escape the immune response. Expression of PD-L1 is a positive predictor of response to immunotherapy; therefore, it should be investigated in TNBC in order to select patients who may benefit from anti-PD-L1 therapies. While many PD-L1 assays are available, only the VENTANA platform with the a...
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#1Begoña VieitesH-Index: 9
#2María Ángeles López-García (ISCIII: Carlos III Health Institute)H-Index: 2
Last. V. Peg (ISCIII: Carlos III Health Institute)H-Index: 1
view all 12 authors...
OBJECTIVE To evaluate the predictive and prognostic value of total tumor load (TTL) in sentinel lymph nodes (SLNs) in patients with infiltrating breast cancer after neoadjuvant systemic therapy (NST). METHODS This retrospective multicenter study used data from a Spanish Sentinel Lymph Node database. Patients underwent intraoperative SLN biopsy after NST. TTL was determined from whole nodes using a one-step nucleic acid amplification (OSNA) assay and defined as the total sum of CK19 mRNA copies i...
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Resumen Introduccion El hallazgo de lesiones de caracteristicas radiologicas indeterminadas y su manejo posterior constituye uno de los principales retos de la patologia mamaria. Lo mismo ocurre ante el diagnostico de entidades histologicas consideradas como de potencial maligno incierto. Los sistemas de categorizacion diagnostica nos ayudan a clasificar estas lesiones, pero poco se sabe sobre la concordancia entre las categorias radiologica e histologica. El objetivo de este estudio es valorar ...
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