Aracelly Quiroz
University of Concepción
PromoterGeneProtein isoformCellular differentiationGene expressionHEK 293 cellsTranscriptional regulationGene isoformComputational biologyBiology
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#1Carlos Farkas (UdeC: University of Concepción)H-Index: 5
#2Aracelly Quiroz (UdeC: University of Concepción)
Last. Roxana Pincheira (UdeC: University of Concepción)H-Index: 18
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The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to cancer. Some studies support a tumor suppressor role and others an oncogenic role for SALL2, which seems to depend on the cancer type. An additional consideration is tissue-dependent expression of different SALL2 isoforms. Human and mouse SALL2 gene loci...
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