Martina Tassinari
University of Milan
Protein–protein interactionPhenotypeFunction (biology)microRNAGene expressionTranscriptomeCell typeNon-coding RNAContext (language use)Cancer-Associated FibroblastsEpigeneticsLong non-coding RNARNAComputational biologyBiologyCell biologyCancer cell
Publications 2
#1Martina Tassinari (University of Milan)
#2Sara N. Richter (UNIPD: University of Padua)H-Index: 33
Last. Paolo Gandellini (University of Milan)H-Index: 25
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Noncoding RNAs are functional transcripts that are not translated into proteins. They represent the largest portion of the human transcriptome and have been shown to regulate gene expression networks in both physiological and pathological cell conditions. Research in this field has made remarkable progress in the comprehension of how aberrations in noncoding RNA drive relevant disease-associated phenotypes; however, the biological role and mechanism of action of several noncoding RNAs still need...
#1Martina Tassinari (University of Milan)
#2Paolo Gandellini (University of Milan)H-Index: 25
Cancer development and progression are not solely cell-autonomous and genetically driven processes. Dynamic interaction of cancer cells with the surrounding microenvironment, intended as the chemical/physical conditions as well as the mixture of non-neoplastic cells of the tumor niche, drive epigenetic changes that are pivotal for the acquisition of malignant traits. Cancer-associated fibroblasts (CAF), namely fibroblasts that, corrupted by cancer cells, acquire a myofibroblast-like reactive phe...