Sao-Keng Mok
Hong Kong Polytechnic University
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#1Sao-Keng Mok (PolyU: Hong Kong Polytechnic University)H-Index: 1
#2Wen-Fang Chen (PolyU: Hong Kong Polytechnic University)H-Index: 8
Last. Man Sau Wong (PolyU: Hong Kong Polytechnic University)H-Index: 35
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Background and purpose: Icariin may be the active ingredient in Herba Epimedii, a Chinese herb commonly used for treatment of osteoporosis. The present study aims to delineate the mechanism(s) by which icariin prevents bone loss after ovariectomy (OVX) in vivo and stimulates osteoblastic functions in vitro. Experimental approach: Ovariectomized or sham-operated C57BL/6 mice were treated with vehicle, 17β-oestradiol or icariin for 6 weeks. Total and trabecular bome mineral density (BMD) as well a...
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