Doudou Hu
Zhejiang University
CancerSupramolecular polymersNanomaterialsNanotechnologyChemistryAdverse effectTumor microenvironmentFunctional polymersImmunotherapyCovalent organic frameworkIron oxide nanoparticlesMetastasisCancer immunotherapyPolymerizationCancer researchVanadiumPolymerGlutathioneBioinformaticsImmune system
Publications 4
#1Xiaodan Xu (ZJU: Zhejiang University)
#2Xiaoxuan Zhou (SRRSH: Sir Run Run Shaw Hospital)H-Index: 4
Last. Jianbin Tang (ZJU: Zhejiang University)H-Index: 31
view all 13 authors...
Liver metastasis (LM) occurs in various cancers, and its early and accurate diagnosis is of great importance. However, the detection of small LMs is still a great challenge because of the subtle differences between normal liver tissue and small metastases. Herein, we prepare glutathione (GSH)-responsive hyaluronic acid-coated iron oxide nanoparticles (HIONPs) for highly sensitive diagnosis of LMs through a facile one-pot method. HIONPs greatly enhance the signal of MRI in tumor metastases as T1 ...
#1Doudou Hu (ZJU: Zhejiang University)H-Index: 2
#2Wei Zhang (ZJU: Zhejiang University)H-Index: 20
Last. Youqing Shen (ZJU: Zhejiang University)H-Index: 63
view all 6 authors...
Abstract Breakthroughs in molecular mechanisms underlying immune-suppressive tumor microenvironment and paradigm shifts in the cancer-immunity response cycle have profoundly changed the landscape of cancer immunotherapy. However, one of the challenges is to mitigate the serious side effects caused by systemic autoimmunity and autoinflammatory responses following immunotherapy. Thus, restraining the activation of the immune system in healthy tissues is highly desirable to address this problem. Bi...
3 CitationsSource
#1Doudou HuH-Index: 2
#2Dongdong LiH-Index: 4
Last. Youqing Shen (ZJU: Zhejiang University)H-Index: 63
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In the past few decades, various vanadium compounds have displayed potential in cancer treatment. However, fast clearness in the body and possible toxicity of vanadium compounds has hindered their further development. Vanadium-based nanomaterials not only overcome these limitations, but take advantage of the internal properties of vanadium in photics and magnetics, which enable them as a multimodal platform for cancer diagnosis and treatment. In this paper, we first introduced the basic biologic...
1 CitationsSource
#1Kaojin Wang (SCUT: South China University of Technology)H-Index: 10
#2Kamran Amin (Center for Excellence in Education)H-Index: 4
Last. Ben Zhong Tang (SCUT: South China University of Technology)H-Index: 128
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The research in advanced functional polymers is being driven by the fast-growing demand of new functional materials for revolutionary technologies. Polymers can be endowed with functions by the use of some special preparation methods or by introducing functional groups or fillers into materials. These functions are either possessed intrinsically by materials or actuated by external stimuli. In this review, we present an overview of the recent developments in research hotspots of functional polym...
28 CitationsSource
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