Seung-Hyun Lee
Seoul National University
CombustionAgricultureInternal medicineGeologyFabricationBusinessLonghorn beetleGenusVirologyNeuroscienceAutomotive engineeringNanotechnologyDendritic spineChemistryMaterials scienceKey (lock)Scrub typhusEscharDiesel engineOrientia tsutsugamushiEnvironmental scienceOptoelectronicsMedicineGroundwaterBiologyZoology
Publications 84
#2Seung-Hyun LeeH-Index: 13
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#1Miso Park (SNU: Seoul National University)H-Index: 4
#1Miso Park (New Generation University College)
Last. Keon Wook Kang (SNU: Seoul National University)H-Index: 59
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Extracellular vesicles (EV) in the tumor microenvironment have emerged as crucial mediators that promote proliferation, metastasis, and chemoresistance. However, the role of circulating small EVs (csEV) in cancer progression remains poorly understood. In this study, we report that csEV facilitates cancer progression and determine its molecular mechanism. csEV strongly promoted the migration of cancer cells via interaction with phosphatidylserine of csEV. Among the three TAM receptors TYRO3, AXL,...
#1Seung-Hyun LeeH-Index: 13
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#1Jiseon Oh (New Generation University College)H-Index: 1
#1Jiseon Oh (SNU: Seoul National University)H-Index: 2
Last. Sun-Won Park (Seoul Metropolitan Government)
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OBJECTIVES Preoperative estimation of the insertion depth angle of cochlear implant (CI) electrodes is essential for surgical planning. The purpose of this study was to determine the cochlear size using preoperative CT and to investigate the correlation between cochlear size and insertion depth angle in morphologically normal cochlea. METHODS Thirty-five children who underwent CI were included in this study. Cochlear duct length (CDL) and the diameter of the cochlear basal turn (distance A/B) on...
1 CitationsSource
The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its critical role in proper neuronal development and function. CYFIP2 is involved in regulating cellular actin dynamics and also interacts with RNA-binding proteins. However, the adult brain function of CYFIP2 remains unclear because investigations thus far are limited to Cyfip2 heterozygous (Cyfip2+/- ) mice owin...
#2Yun-Jung ChoiH-Index: 25
#1Gyu Hyun KimH-Index: 2
#1Gyu Hyun KimH-Index: 1
Last. Kihoon Han (KU: Korea University)H-Index: 17
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Variants of the cytoplasmic FMR1-interacting protein (CYFIP) gene family, CYFIP1 and CYFIP2, are associated with numerous neurodevelopmental and neuropsychiatric disorders. According to several studies, CYFIP1 regulates the development and function of both pre- and post-synapses in neurons. Furthermore, various studies have evaluated CYFIP2 functions in the postsynaptic compartment, such as regulating dendritic spine morphology; however, no study has evaluated whether and how CYFIP2 affects pres...
#1Seung-Hyun Lee (SNU: Seoul National University)H-Index: 13
#2Yinhua Zhang (KU: Korea University)H-Index: 9
Last. Kihoon Han (KU: Korea University)H-Index: 17
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OBJECTIVE Genetic variants of the cytoplasmic FMR1-interacting protein 2 (CYFIP2) encoding an actin-regulatory protein are associated with brain disorders, including intellectual disability and epilepsy. However, specific in vivo neuronal defects and potential treatments for CYFIP2-associated brain disorders remain largely unknown. Here, we characterized Cyfip2 heterozygous (Cyfip2+/- ) mice to understand their neurobehavioral phenotypes and underlying pathological mechanisms. Furthermore, we ex...
2 CitationsSource
#1Min Hyeuk Lee (SNU: Seoul National University)H-Index: 1
#2Seung-Hyun Lee (SNU: Seoul National University)H-Index: 13
Last. Seunghwan Lee (SNU: Seoul National University)H-Index: 32
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Abstract The subfamily Cryptarchinae Thomson, 1859 from Korea is partly reviewed. This study is the first part of the revision, treating two genera: Glischrochilus Reitter, 1873 and Pityophagus Shuckard, 1839. Three species, Glischrochilus (Librodor) binaevus (Reitter, 1879), Glischrochilus (Glischrochilus) cruciatus (Motschulsky, 1860), and Pityophagus basalis Reitter, 1874 are newly reported for the first time in Korea. Descriptions, photographs of external morphology and genital structures, b...