Silvia Carrara
Vita-Salute San Raffaele University
Internal medicineRadiologySurgeryPathologyRandomized controlled trialProspective cohort studyBiopsyPancreatitisIntraductal papillary mucinous neoplasmColonoscopyEndoscopyPancreasSampling (medicine)Pancreatic cancerEndoscopic ultrasoundIn patientConfidence intervalGeneral surgeryMedicineGastroenterology
Publications 166
#1Silvia CarraraH-Index: 20
#2Marco Spadaccini (Humanitas University)H-Index: 14
Last. Alessandro Repici (Humanitas University)H-Index: 71
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#1G. Peduzzi (UniPi: University of Pisa)
#2Manuel Gentiluomo (UniPi: University of Pisa)H-Index: 6
Last. Luca Morelli (UniPi: University of Pisa)H-Index: 21
view all 68 authors...
BACKGROUND The mitochondrial metabolism has been associated with pancreatic ductal adenocarcinoma (PDAC) risk. Recent evidence also suggests the involvement of the genetic variability of the mitochondrial function in several traits involved in PDAC etiology. However, a systematic investigation of the genetic variability of mitochondrial genome (mtSNP) and of all the nuclear genes involved in its functioning (n-mtSNPs) has never been reported. METHODS We conducted a two-phase association study of...
#1Ye Lu (DKFZ: German Cancer Research Center)
#5George Theodoropoulos (UoA: National and Kapodistrian University of Athens)H-Index: 31
Last. Jakob R. Izbicki (UHH: University of Hamburg)H-Index: 75
view all 77 authors...
#1Marco Spadaccini (Humanitas University)H-Index: 14
#2Andrea Iannone (University of Bari)H-Index: 15
Last. Piera Alessia GaltieriH-Index: 9
view all 22 authors...
Summary null null Background null Computer-aided detection (CADe) techniques based on artificial intelligence algorithms can assist endoscopists in detecting colorectal neoplasia. CADe has been associated with an increased adenoma detection rate, a key quality indicator, but the utility of CADe compared with existing advanced imaging techniques and distal attachment devices is unclear. null null null Methods null For this systematic review and network meta-analysis, we did a comprehensive search...
#1Alessandro Repici (Humanitas University)H-Index: 71
#2Annalisa Cappello (Humanitas University)H-Index: 4
Last. Matteo Badalamenti (Humanitas University)H-Index: 4
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Introduction null Multiple therapeutic modalities including surgery and rigid and flexible endoscopy have been adopted to manage Zenker's diverticulum (ZD). Minimally invasive flexible endoscopic septotomy (FES) techniques have been increasingly favored over the past 20 years; however, long-term data are still scanty. The aim of this study is to evaluate early and long-term outcomes of FES for naive ZD in a single-center setting. null Methods null From 2010 to 2017, ZD patients treated with FES ...
#1Ferdinando D'Amico (Humanitas University)H-Index: 14
#2Arnaldo AmatoH-Index: 22
Last. Alessandro Repici (Humanitas University)H-Index: 71
view all 27 authors...
ABSTRACT Background and aims Granular mixed laterally spreading tumors (GM-LSTs) have an intermediate level of risk for submucosal invasive cancer (SMICs) without clear signs of invasion (covert); the optimal resection method is uncertain. We aimed to determine the risk of covert SMIC in GM-LSTs based on clinical and endoscopic factors. Methods We collected data from 693 patients (50.6% male; median age, 69 years) with colorectal GM-LSTs, without signs of invasion, who underwent endoscopic resec...
5 CitationsSource
#1Francesca GavazziH-Index: 12
#2Giovanni Capretti (Humanitas University)H-Index: 16
Last. Alessandro Zerbi (Humanitas University)H-Index: 57
view all 10 authors...
Abstract null null Background null It is unclear whether invasive intraductal papillary mucinous neoplasm (IPMN) has different clinical and prognostic characteristics, beyond histological factors, when compared to pancreatic ductal adenocarcinoma (PDAC). null null null Aims null compare prognostic features of resected PDAC and invasive IPMN null null null Methods null A retrospective study of patients resected for PDAC or invasive IPMN realized at Humanitas Cancer Center's Pancreatic Surgery Uni...
BACKGROUND AND AIMS Artificial intelligence has been shown to increase adenoma detection rate (ADR) as the main surrogate outcome parameter of colonoscopy quality. To which extent this effect may be related to physician experience is not known. We performed a randomised trial with colonoscopists in their qualification period (AID-2) and compared these data with a previously published randomised trial in expert endoscopists (AID-1). METHODS In this prospective, randomised controlled non-inferiori...
1 CitationsSource
#2Roberto Di MitriH-Index: 11
Last. Gloria Fernández-Esparrach (University of Barcelona)H-Index: 33
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ABSTRACT null null Background and aims null Benefit of rapid on-site evaluation (ROSE) on diagnostic accuracy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) has never been evaluated in a randomized study. This trial aimed to test the hypothesis that in solid pancreatic lesions (SPLs), diagnostic accuracy of EUS-FNB without ROSE was not inferior to that of EUS-FNB with ROSE. null null null Methods null Non-inferiority study (non-inferiority margin 5%) conducted at 14 centers in eigh...
12 CitationsSource
#1Marco Spadaccini (Humanitas University)H-Index: 14
Last. Piera Alessia GaltieriH-Index: 9
view all 20 authors...
Background null The novel Coronavirus (SARS-CoV-2) has caused almost 2 million deaths worldwide. Both Food and Drug Administration and European Medicines Agency have recently approved the first COVID-19 vaccines, and a few more are going to be approved soon. null Methods null Several different approaches have been used to stimulate the immune system in mounting a humoral response. As more traditional approaches are under investigation (inactivated virus vaccines, protein subunit vaccines, recomb...