Cong-Shan Yuan
Ocean University of China
Self-healing hydrogelsWarburg effectCancerIntensive care medicineNanocarriersBiochemical engineeringChemistryReuseAllergyPsychological interventionAsthmaFish scaleNatural (archaeology)BiocompatibilityImmunotherapyImmunogenic cell deathCancer vaccineBiomaterialDrug deliveryCancer immunotherapyImmune checkpointImmunogenicityPhysical traumaDrug accumulationCancer therapyDelivery systemCartilage repairBurn dressingCell scaffoldWound managementBurn woundAllergen avoidanceDrug releaseTissue engineeringPharmacotherapyCancer researchMonoclonal antibodyMedicineNasal administrationImmune system
5Publications
1H-index
7Citations
Publications 6
Newest
#1Di QinH-Index: 2
#2Bi ShichaoH-Index: 1
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#1Ying-Xia Yao (Ocean University of China)H-Index: 1
#2Andi Zhang (Ocean University of China)H-Index: 2
Last. Ya Liu (Ocean University of China)H-Index: 21
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Acute and chronic wounds can cause severe physical trauma to patients and also result in an immense socio-economic burden. Thus, wound management has attracted increasing attention in recent years. However, burn wound management is still a major challenge in wound management. Autografts are often considered the gold-standard for burn care, but their application is limited by many factors. Hence, ideal burn dressings and skin substitute dressings are desirable. With the development of biomaterial...
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#1Zhenwei Deng (Ocean University of China)H-Index: 1
#2Cong-Shan Yuan (Ocean University of China)H-Index: 1
Last. Ya Liu (Ocean University of China)H-Index: 21
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Abstract In recent years, with the continuous development of cancer immunotherapy, the strategy of human beings against cancer has undergone tremendous changes. Among them, immune checkpoint inhibitors based on the immune "brake" mechanism, as an indispensable part of immunotherapy, have brought new dawn to cancer treatment. Humans have developed a variety of monoclonal antibodies against CTLA-4 and PD-1/PD-L1, which have shown significant therapeutic effects on various cancers, especially melan...
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Allergy, IgE-mediated inflammatory disorders including allergic rhinitis, asthma, and conjunctivitis, affects billions of people worldwide. Conventional means of allergy management include allergen avoidance, pharmacotherapy, and emerging therapies. Among them, chemotherapeutant intake via oral, intravenous, and intranasal routes is always the most common mean. Although current pharmacotherapy exhibit splendid anti-allergic effects, short in situ retention, low bioavailability, and systemic side...
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#1Cong-Shan Yuan (Ocean University of China)H-Index: 1
#2Zhenwei Deng (Ocean University of China)H-Index: 1
Last. Ya Liu (Ocean University of China)H-Index: 21
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Abstract The past several years have witnessed the blooming of emerging immunotherapy, as well as their therapeutic potential in remodeling the immune system. Nevertheless, with the development of biological mechanisms in oncology, it has been demonstrated that hypoxic tumor microenvironment (TME) seriously impairs the therapeutic outcomes of immunotherapy. Hypoxia, caused by Warburg effect and insufficient oxygen delivery, has been considered as a primary construction element of TME and drawn t...
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#1Cong-Shan Yuan (Ocean University of China)H-Index: 1
#2Ya Liu (Ocean University of China)H-Index: 21
Last. Xiguang Chen (Ocean University of China)H-Index: 61
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Immunomodulatory therapeutics, which is conducive to overcoming tumor tolerance and restoring normal immune responses, has been proposed as a promising approach for enhanced cancer therapy and clin...
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