Suneel Kumar
Rutgers University
RapidityPhysicsNeutronNucleonAtomic physicsNuclear physicsEnergy (signal processing)IsospinNuclear reactionSpinal cord injuryFragmentation (mass spectrometry)Range (particle radiation)Flow (mathematics)AsymmetrySymmetry (physics)Cross section (physics)Equation of stateMomentumMedicineImpact parameter
177Publications
18H-index
1,333Citations
Publications 221
Newest
#1Oak Z. Chi (RU: Rutgers University)H-Index: 19
#2Thomas Theis (RU: Rutgers University)H-Index: 6
Last. Harvey R. Weiss (RU: Rutgers University)H-Index: 26
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OBJECTIVE Neural cell adhesion molecule L1CAM (L1) is involved in neuroprotection. To investigate a possible neuroprotective effect of L1 during ischemia, we determined whether blocking L1 with an antagonistic antibody would worsen the outcome of focal cerebral ischemia-reperfusion and increase blood-brain barrier (BBB) disruption. METHODS Transient middle cerebral artery occlusion (MCAO) was performed in anesthetized rats. Five µg of antagonistic mouse IgG monoclonal L1 antibody 324 or non-immu...
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#2Suneel KumarH-Index: 18
Last. Indu Pal KaurH-Index: 40
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The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure homogenization, without using organic solvents, were optimized using the Taguchi design followed by the central composite design. The optimized CSLNs exhibited a high assay/drug content (0.6% w/w), solubility (6 × 105 times), and EE (75%) with a particle size < 200 nm (PDI—0.143). The CSLNs were safe (in vitro and in vivo), photost...
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#1Hwan June Kang (RU: Rutgers University)H-Index: 2
#2Suneel Kumar (RU: Rutgers University)H-Index: 18
Last. Francois Berthiaume (RU: Rutgers University)H-Index: 53
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Abstract Chronic and non-healing skin wounds are some of the most significant complications in patients with advanced diabetes. A contributing mechanism to this pathology is the non-enzymatic glycation of proteins due to hyperglycemia, leading to the formation of advanced glycation end products (AGEs). AGEs bind to the receptor for AGEs (RAGE), which triggers pro-inflammatory signals that may inhibit the proliferative phase of wound healing. Soluble forms of RAGE (sRAGE) may be used as a competi...
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#1Suneel KumarH-Index: 18
#2Yuying TanH-Index: 5
Last. Francois BerthiaumeH-Index: 53
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Pressure ulcers (PUs) or sores are a secondary complication of diabetic neuropathy and traumatic spinal cord injury (SCI). PUs tend to occur in soft tissues located around bony prominences and may heal slowly or not at all. A common mechanism underlying impaired healing of PUs may be dysfunction of the local neurovascular system including deficiency of essential neuropeptides, such as substance P (SP). Previous studies indicate that disturbance in cutaneous sensory innervation leads to a defect ...
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#1Abdul Haque Ansari (Texila American University)
#2Ajay Pal (CUMC: Columbia University Medical Center)
Last. Suneel Kumar (RU: Rutgers University)H-Index: 18
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Fibromyalgia is a musculoskeletal pain of different parts of the body, which is also associated with fatigue, lack of sleep, cognition deficits, family history, gender bias, and other disorders such as osteoarthritis and rheumatoid arthritis. It is generally initiated after trauma, surgery, infection, or stress. Fibromyalgia often coexists with several other conditions or disorders such as temporomandibular joint disorders, bowel and bladder syndrome, anxiety, depression, headaches, and intersti...
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#1Rohan Chawla (AIIMS: All India Institute of Medical Sciences)H-Index: 13
#2Suneel Kumar (AIIMS: All India Institute of Medical Sciences)H-Index: 18
Last. Shreyans Jain (AIIMS: All India Institute of Medical Sciences)H-Index: 3
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Objective:To describe the retinal imaging characteristics, retinopathy management strategies and visual outcomes in cases of diabetes with chronic myeloid leukaemia.Design:Retrospective observation...
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#1Anika HaqH-Index: 5
#2Suneel Kumar (RU: Rutgers University)H-Index: 18
Last. Bozena Michniak-KohnH-Index: 27
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The purpose of this study was to synthesize and characterize novel biocompatible topical polymeric film and hydrogel systems that have the potential to deliver the antibacterial agent thymoquinone (TQ) directly to the skin target site to manage the local wound infection and thereby wound healing. The polyvinyl pyrrolidone (PVP) matrix-type films containing TQ were prepared by the solvent casting method. In vitro skin permeation studies on human cadaver skin produced a mean flux of 2.3 µg TQ/cm2/...
2 CitationsSource
#1Thomas Theis (RU: Rutgers University)H-Index: 6
#2Suneel Kumar (RU: Rutgers University)H-Index: 18
Last. Melitta Schachner (RU: Rutgers University)H-Index: 152
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Myristoylated alanine-rich C-kinase substrate (MARCKS) is an intracellular receptor for polysialic acid. MARCKS supports development, synaptic plasticity, and regeneration after injury. MARCKS binds with its functionally essential effector domain (ED) to polysialic acid. A 25-mer peptide comprising the ED of MARCKS stimulates neuritogenesis of primary hippocampal neurons after addition to the culture. This motivated us to investigate whether ED peptide has similar effects in spinal cord injury. ...
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#1Paulina Krzyszczyk (RU: Rutgers University)H-Index: 4
#2Hwan June Kang (RU: Rutgers University)H-Index: 2
Last. Francois Berthiaume (RU: Rutgers University)H-Index: 53
view all 11 authors...
: Nonhealing wounds possess elevated numbers of pro-inflammatory M1 macrophages, which fail to transition to anti-inflammatory M2 phenotypes that promote healing. Hemoglobin (Hb) and haptoglobin (Hp) proteins, when complexed (Hb-Hp), can elicit M2-like macrophages through the heme oxygenase-1 (HO-1) pathway. Despite the fact that nonhealing wounds are chronically inflamed, previous studies have focused on non-inflammatory systems, and do not thoroughly compare the effects of complexed vs individ...
2 CitationsSource
Purpose To describe the use of glycerine in improving media clarity in cases with edematous cornea. Methods Retrospective case-series including patients with posterior segment pathologies needing surgical invention and having corneal edema. Each case was studied for the role of topical application of glycerine instead of viscoelastic agents and the course of surgery. The cases were followed up for minimum 3-months duration. Results Six cases with corneal edema having posterior segment pathology ...
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