Guang-Sen Shi
Shanghai Jiao Tong University
Biomedical engineeringBone remodelingChemistryBiocompatibilityPLGABone regenerationBone resorptionOsteoidBone healingScaffold
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#1Guang-Sen Shi (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Ying-Ying Li (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last. Shihui Chen (CUHK: The Chinese University of Hong Kong)H-Index: 11
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Abstract Background/objectives For treatment of large bone defects challenging in orthopaedic clinics, bone graft substitutes are commonly used for the majority of surgeons. It would be proposed in the current study that our bioactive scaffolds could additionally serve as a local delivery system for therapeutic small molecule agents capable of providing support to enhance biological bone repair. Methods In this study, composite scaffolds made of poly (lactic-co-glycolic acid) (PLGA) and tricalci...
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