Bavani Subramaniam
University of Malaya
Pharmaceutical formulationCancerTargeted drug deliveryNanomedicineCytotoxic T cellBioavailabilityBiochemical engineeringChemistryMaterials scienceSolid lipid nanoparticleIn vitroIn vivoAlpinia conchigeraDrug deliveryDrugProstate cancerNanoparticle TypeDesign of experimentsCancer cellPharmacology
Publications 2
#1Bavani SubramaniamH-Index: 1
Last. Noor Hasima NagoorH-Index: 11
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1′-acetoxychavicol acetate (ACA) extracted from the rhizomes of Alpinia conchigera Griff (Zingiberaceae) has been shown to deregulate the NF-ĸB signaling pathway and induce apoptosis-mediated cell death in many cancer types. However, ACA is a hydrophobic ester, with poor solubility in an aqueous medium, limited bioavailability, and nonspecific targeting in vivo. To address these problems, ACA was encapsulated in a nanostructured lipid carrier (NLC) anchored with plerixafor octahydrochloride (AMD...
#1Bavani Subramaniam (UM: University of Malaya)H-Index: 1
#2Zahid H. Siddik (University of Texas MD Anderson Cancer Center)H-Index: 35
Last. Noor Hasima Nagoor (UM: University of Malaya)H-Index: 11
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Lipid-based nanoparticles for drug delivery have been employed in the development of nanomedicine for various applications. One such versatile nanoparticle type is nanostructured lipid carriers (NLCs) that include multiple combinations of lipids and drugs for diverse routes of administrations. Optimization of NLCs to achieve ideal particle size distribution, dispersion in the aqueous environment, long-term stability, drug protection ability, and targeting features is necessary for designing impr...
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