Veerbhan Kesarwani
Allahabad University
GeneInfectivityGlycoproteinHost (biology)Innate immune systemAntigenVirologyTranscriptomeNanoprobeVitronectinReceptorMHC class IGene expression profilingChemistryEpitopeCell surface receptorMajor histocompatibility complexBinding domainVirusIn silicoPathogenPeptideDrug deliveryImmunogenicitySomatomedin BNanoconjugatesPopulationBiochemistryUrokinase receptorViral entryComputational biologyBiologyImmune systemPhylogenetics
Publications 3
#1Deepshikha ShahdeoH-Index: 4
#2Veerbhan KesarwaniH-Index: 1
Last. Sonu GandhiH-Index: 19
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Abstract Targeting cell surface receptors for specific drug delivery in cancer has garnered lot of attention. Urokinase plasminogen activator receptor (uPAR), a surface biomarker, is overexpressed on many tumours including breast, colorectal, prostate, and ovarian cancers. Binding of growth factor domain (GFD) of urokinase plasminogen activator (uPA) with uPAR lead to its close conformation, and allow somatomedin B domain (SMB) of vitronectin binding by allosteric modulation. In-silico docking o...
#2Priyanka GargH-Index: 2
Last. Trilochan Mohapatra (ICAR: Indian Council of Agricultural Research)H-Index: 46
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Background: SARS-CoV-2 is a viral pathogen causing life-threatening disease in human. Interaction between spike protein of SARS-CoV-2 and ACE2 receptor on the cells is a potential factor in the infectivity of a host. The interaction of SARS-CoV-2 spike receptor-binding domain with its receptor - ACE2, in different hosts was evaluated to understand and predict viral entry. The protein and nucleotide sequences of ACE2 were initially compared across different species to identify key differences amo...
#2Veerbhan Kesarwani (Allahabad University)H-Index: 1
Last. Shailesh N. SharmaH-Index: 22
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Genomics-led researches are engaged in tracing virus expression pattern, and induced immune responses in human to develop effective vaccine against COVID-19. In this study, targeted expression profiling and differential gene expression analysis of major histocompatibility complexes and innate immune system genes were performed through SARS-CoV-2 infected RNA-seq data of human cell line, and virus transcriptome was generated for T-and B-cell epitope prediction. Docking studies of epitopes with MH...
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