Priyanka Garg
Indian Institute of Science
GeneInfectivityGlycoproteinLivestockFusion proteinHost (biology)microRNAVirologyTranscriptomeReceptorAvidityChemistryBinding domainVirusT cellPathogenCR6261CoronavirusNewcastle diseaseB cellHamsterImmunogenHost responseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Binding abilityGeneticsViral entryQuantitative trait locusTranscription factorBiologyImmune systemPhylogenetics
5Publications
2H-index
5Citations
Publications 5
Newest
Long non-coding RNAs (lncRNAs) are the transcripts of length longer than 200 nucleotides. They are involved in the regulation of various biological activities. Leghorn and Fayoumi breeds of Gallus gallus were known to be having differential resistance against Newcastle Disease Virus (NDV) infection. Differentially expressed genes which were thought to be involved in this pattern of resistance were already studied. Here we report the analysis of the transcriptomic data of Harderian gland of Gallu...
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#1U. Kar (IISc: Indian Institute of Science)
#1Uddipan Kar (IISc: Indian Institute of Science)H-Index: 1
Last. Raghavan VaradarajanH-Index: 38
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Influenza is a highly contagious virus, belonging to the family Orthomyxovirus that causes acute febrile respiratory illness which may even be fatal in some cases. Self-assembling protein nanoparticles have been used to display several copies of an immunogen, thus enhancing B cell and T cell immune responses through avidity effects. Using an iterative structure-guided approach, we successfully displayed twelve copies of a previously designed influenza stem domain immunogen pH1HA10 on the ferriti...
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#2Priyanka GargH-Index: 2
Last. Trilochan Mohapatra (ICAR: Indian Council of Agricultural Research)H-Index: 46
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Background: SARS-CoV-2 is a viral pathogen causing life-threatening disease in human. Interaction between spike protein of SARS-CoV-2 and ACE2 receptor on the cells is a potential factor in the infectivity of a host. The interaction of SARS-CoV-2 spike receptor-binding domain with its receptor - ACE2, in different hosts was evaluated to understand and predict viral entry. The protein and nucleotide sequences of ACE2 were initially compared across different species to identify key differences amo...
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#2Priyanka GargH-Index: 2
Last. Trilochan Mohapatra (ICAR: Indian Council of Agricultural Research)H-Index: 46
view all 12 authors...
Background: SARS-CoV-2 is a viral pathogen causing life threatening disease in human. Interaction between spike protein of SARS-CoV-2 and ACE2 receptor on the cells is a potential factor in the infectivity of a host. The interaction of SARS-CoV-2 spike receptor-binding domain with its receptor - ACE2, in different hosts was evaluated to understand and predict viral entry. The protein and nucleotide sequences of ACE2 were initially compared across different species to identify key differences amo...
1 CitationsSource
#2Priyanka GargH-Index: 2
Last. Trilochan Mohapatra (ICAR: Indian Council of Agricultural Research)H-Index: 46
view all 12 authors...
SARS-CoV-2 is a viral pathogen causing life threatening disease in human. Interaction between spike protein of SARS-CoV-2 and ACE2 receptor on the cells is a potential factor in the infectivity of a host. Using in-silico analysis, the protein and nucleotide sequences of ACE2 were initially compared across different species to identify key differences among them. This phylogeny and alignment comparison did not lead to any meaningful conclusion on viral entry facilitation in different hosts. The 6...
1 CitationsSource