Songfeng Chen
Sun Yat-sen University
Internal medicineCardiothoracic surgeryRetrospective cohort studyBasal (phylogenetics)DysplasiaBiopsyRelaxation (psychology)HeartburnIntestinal metaplasiaPharynxGERDLeukoplakiaEsophagusEndoscopyDiseaseEsophageal pH monitoringContext (language use)Surgical oncologyBody mass indexLarynxDysphagiaLaryngopharyngeal refluxEsophageal motility disorderProton-pump inhibitorEsophagogastroscopyErosive esophagitisEsophageal peristalsisDecision curve analysisOlder patientsIn patientBaseline impedanceEsophagogastric junctionTreatment methodNomogramAnesthesiaRefluxHistologyClinical significanceMedicineGastroenterology
4Publications
1H-index
1Citations
Publications 7
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#1Songfeng Chen (SYSU: Sun Yat-sen University)H-Index: 1
#2Mengyu Zhang (SYSU: Sun Yat-sen University)H-Index: 4
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
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#1Songfeng Chen (SYSU: Sun Yat-sen University)H-Index: 1
#2Mengyu Zhang (SYSU: Sun Yat-sen University)H-Index: 4
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
view all 0 authors...
INTRODUCTION Achalasia is a primary esophageal motility disorder with heterogeneous manometric subtypes and prognosis, characterized by degeneration of the esophageal myenteric plexus, and reduction in interstitial cells of Cajal (ICCs). This study aimed to explore the histopathologic characteristics of lower esophageal sphincter (LES) muscle from patients with achalasia with different subtypes and different prognosis. METHODS We examined specimens of LES muscle from 122 patients with achalasia ...
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#1Qianjun Zhuang (SYSU: Sun Yat-sen University)
#2Niandi Tan (SYSU: Sun Yat-sen University)H-Index: 2
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
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BACKGROUND The updated Chicago Classification version 4.0 (CCv4.0) establishes a more stringent criteria to diagnose ineffective esophageal motility (IEM). This study aims to investigate the clinical significance of IEM in CCv4.0 in the context of gastroesophageal reflux disease (GERD). METHODS A retrospective study was conducted among suspected GERD patients who had heartburn and/or regurgitation as their chief complaints and completed esophageal function tests in our center from 2017 to 2019. ...
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#1Songfeng Chen (SYSU: Sun Yat-sen University)H-Index: 1
#2Mengya Liang (SYSU: Sun Yat-sen University)H-Index: 1
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
view all 8 authors...
Background/Aims Esophagogastric junction outflow obstruction (EGJOO) is characterized by elevated integrated relaxation pressure (IRP) and preserved esophageal peristalsis. The clinical significance of EGJOO is uncertain. This study aim to describe the clinical characteristics of these patients and to find out potential parameters to predict patients' symptom outcome. Methods Consecutive patients who received high-resolution manometry examination in our hospital in 2013-2019 and met the diagnost...
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#1Mengyu Zhang (SYSU: Sun Yat-sen University)H-Index: 4
#2Mengya Liang (SYSU: Sun Yat-sen University)H-Index: 1
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
view all 6 authors...
Most of patients with erosive esophagitis (EE) are of LA grade AB 0.839 (95% CI 0.678–0.995), respectively]. Decision curves showed significant clinical usefulness. The first physiologic nomogram was developed to discriminate the individualized response to PPI therapy among EE patients.
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#1Yuqing Lin (SYSU: Sun Yat-sen University)H-Index: 1
#2Yuwen Li (SYSU: Sun Yat-sen University)H-Index: 7
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
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Background/Aims There is less acid burden in Chinese gastroesophageal reflux disease (GERD) patients. However, the Lyon consensus proposed a higher threshold of acid exposure time (AET > 6%) for GERD. The aims are to apply the updated criteria in Chinese GERD patients and clarify its influence on clinical outcome. Methods Patients who were referred for both esophageal high-resolution manometry and 24-hour esophageal pH monitoring due to reflux symptoms were retrospectively screened. Those patien...
1 CitationsSource
#1Songfeng Chen (SYSU: Sun Yat-sen University)H-Index: 1
#2Mengya Liang (SYSU: Sun Yat-sen University)H-Index: 1
Last. Yinglian Xiao (SYSU: Sun Yat-sen University)H-Index: 9
view all 7 authors...
BACKGROUND AND AIM: Laryngopharyngeal reflux (LPR) is caused by the reflux of gastric contents beyond the esophagus into the larynx and pharynx. However, upper esophageal sphincter (UES) motility and proximal esophagus reflux parameters are poorly studied. This study aims to explore the characteristics of UES motility and reflux parameter among LPR patients. METHODS: Patients with laryngopharyngeal symptoms only (L), patients with laryngopharyngeal symptoms and typical esophageal symptoms (L + E...
2 CitationsSource