Yuhe Yang
Hong Kong Polytechnic University
CancerBiomedical engineeringHeat-affected zoneArc blowComposite materialControlled releaseShielded metal arc weldingNanotechnologyMetallurgyMaterials scienceWeldingArc weldingBiocompatibilityDrug deliveryBone regenerationTissue engineeringMedicineScaffoldNanocompositeCancer cell
14Publications
4H-index
73Citations
Publications 14
Newest
#1Yuhe Yang (PolyU: Hong Kong Polytechnic University)H-Index: 4
#2Tianpeng Xu (PolyU: Hong Kong Polytechnic University)H-Index: 1
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
view all 6 authors...
Current periosteal grafts have limitations related to low mechanical strength, tissue adhesiveness, and poor osteogenesis and angiogenesis potential. Here, a periosteum mimicking bone aid (PMBA) with similar structure and function to natural periosteum is developed by electrospinning photocrosslinkable methacrylated gelatin (GelMA), l-arginine-based unsaturated poly(ester amide) (Arg-UPEA), and methacrylated hydroxyapatite nanoparticles (nHAMA). Such combination of materials enhances the materia...
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#1Long Xiao (Nanjing University of Chinese Medicine)
#1Long XiaoH-Index: 3
Last. Zhirong Wang (Nanjing University of Chinese Medicine)H-Index: 6
view all 12 authors...
Cytomembrane cancer nanovaccines are considered a promising approach to induce tumor-specific immunity. Most of the currently developed nanovaccines, unfortunately, fail to study the underlying mechanism for cancer prevention and therapy, as well as immune memory establishment, with their long-term anti-tumor immunity remaining unknown. Here, we present a strategy to prepare biomimetic cytomembrane nanovaccines (named CCMP@R837) consisting of antigenic cancer cell membrane (CCM)-capped poly(lact...
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#1Zhijun Ma (PolyU: Hong Kong Polytechnic University)H-Index: 38
#2Qiyao Huang (PolyU: Hong Kong Polytechnic University)H-Index: 11
Last. Zijian Zheng (PolyU: Hong Kong Polytechnic University)H-Index: 53
view all 11 authors...
Stretchable electronics find widespread uses in a variety of applications such as wearable electronics, on-skin electronics, soft robotics and bioelectronics. Stretchable electronic devices conventionally built with elastomeric thin films show a lack of permeability, which not only impedes wearing comfort and creates skin inflammation over long-term wearing but also limits the design form factors of device integration in the vertical direction. Here, we report a stretchable conductor that is fab...
3 CitationsSource
#1Qiang Zhang (PolyU: Hong Kong Polytechnic University)H-Index: 8
#2Yuhe Yang (PolyU: Hong Kong Polytechnic University)H-Index: 4
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
view all 5 authors...
Abstract Tendon adhesion formation describes the development of fibrotic tissue between the tendon and its surrounding tissues, which commonly occurs as a reaction to injury or surgery. Its impact on function and quality of life varies from negligible to severely disabling, depending on the affected area and extent of adhesion formed. Thus far, treatment options remain limited with prophylactic anti-inflammatory medications and revision surgeries constituting the only tools within the doctors’ a...
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#1Jingdong Rao (PolyU: Hong Kong Polytechnic University)H-Index: 2
#2Yuhe Yang (PolyU: Hong Kong Polytechnic University)H-Index: 4
Last. Xin ZhaoH-Index: 45
view all 5 authors...
Bacteria and cancer cells share a unique symbiotic relationship in the process of cancer development and treatment. It has been shown that certain bacteria can mediate cancer and thrive inside cancerous tissues. Moreover, during cancer treatment, microbial infections have been shown to impair the therapeutic efficacy and lead to serious complications. In the past decades, the application of antibiotics has achieved great success in fighting numerous bacteria but the administration route, low loc...
1 CitationsSource
#1Yuhe Yang (PolyU: Hong Kong Polytechnic University)H-Index: 4
#2Qiang Zhang (PolyU: Hong Kong Polytechnic University)H-Index: 8
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
view all 9 authors...
Abstract 3D printing is known as a cost-effective technique that shows huge potential in fabrication of graft substitutes for bone tissue regeneration. However, the tradeoff between 3D printability, mechanical strength and bioactivity of the printed materials (i.e., inks) remains a challenge. In this work, we present a novel photocrosslinkable nanocomposite ink composed of tri-block poly (lactide-co-propylene glycol-co-lactide) dimethacrylate (PmLnDMA, m and n respectively represent the unit len...
4 CitationsSource
#1Jingdong Rao (PolyU: Hong Kong Polytechnic University)H-Index: 2
#2Ho Pan Bei (PolyU: Hong Kong Polytechnic University)H-Index: 3
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
view all 6 authors...
Cardiovascular stenting is an effective method for treating cardiovascular diseases (CVDs), yet thrombosis and restenosis are the two major clinical complications that often lead to device failure. Nitric oxide (NO) has been proposed as a promising small molecule in improving the clinical performance of cardiovascular stents thanks to its anti-thrombosis and anti-restenosis ability, but its short half-life limits the full use of NO. To produce NO at lesion site with sufficient amount, NO-produci...
1 CitationsSource
#1Wenqing He (CityU: City University of Hong Kong)H-Index: 7
#2Zhaoyue Wang (CityU: City University of Hong Kong)H-Index: 6
Last. Xi Yao (CityU: City University of Hong Kong)H-Index: 36
view all 9 authors...
Inspired by the mucus, which provides an ideal supramolecular model and whose fluid-like (viscous) and solid-like (elastic) behaviors can be adjusted to meet different physiological requirements, w...
8 CitationsSource
#1Yuanchi Zhang (PolyU: Hong Kong Polytechnic University)H-Index: 4
#2Jinlian Hu (PolyU: Hong Kong Polytechnic University)H-Index: 62
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
view all 9 authors...
Abstract The use of a screw for repairing defected bones is limited by the dilemma between stiffness, bioactivity and internal fixation ability in current products. For polymer bone screw, it is difficult to achieve the bone stiffness and osteo-induction. Polymer composites may enhance bioactivity and mechanical properties but sacrifice the shape memory properties enormously. Herein, we fabricated a programmable bone screw which is composed of shape memory polyurethane, hydroxyapatite and arginy...
3 CitationsSource
#1Bin Wu (NUS: National University of Singapore)H-Index: 12
#2Yuhe Yang (NUS: National University of Singapore)H-Index: 1
Last. Jerry Y. H. Fuh (NUS: National University of Singapore)H-Index: 64
view all 8 authors...
Abstract Specific structures of esophagus play an important role in specific functions. However, current esophageal tissue engineering scaffolds replicate them poorly. To address this issue, the objective of this study is to fabricate a hierarchical PCL/F127 scaffold inspired by the natural esophageal structure. The hierarchical scaffold consists of aligned fibers in micro-size and thin film with nano-sized pores through combining E-jetting and E-spraying. The aligned fibers of scaffold guide th...
3 CitationsSource