Liang Kong
Akt/PKB signaling pathwayCaspase 3Molecular biologyRanReporter geneGene knockdownKinaseChemistryTUNEL assayPropidium iodideWestern blotFluorescein isothiocyanatePTENGlucose uptakeTensinProtein kinase BPI3K/AKT/mTOR pathwayAnnexinCell biology
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#1Yinming WangH-Index: 1
#2Junquan GuH-Index: 1
Last. Shuhua GuiH-Index: 1
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Effect of micro ribonucleic acid (miR)-130a on neuronal apoptosis in rats with cerebral infarction (CI) was studied to explore whether phosphatase and tensin homolog deleted on chromosome ten (PTEN)/phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (Akt) is involved in the regulation of neuronal apoptosis. Thirty-six Sprague-Dawley (SD) rats were randomly divided into blank control group, model group and miR-130a low-expression group. miR-130a was determined by quantitative polymeras...
7 CitationsSource
#1Junquan GuH-Index: 1
#2Shuhua GuiH-Index: 1
Last. Yinming WangH-Index: 1
view all 6 authors...
Differentially expressed miRNAs in the GEO profile of ischemic stroke were analyzed to clarify the specific role of microRNA-324-5p (miRNA-324-5p) in ischemic stroke and the potential mechanism. After screening out miRNA-324-5p, its level in peripheral blood of stroke patients and in vitro oxygen-glucose deprivation (OGD)-induced primary rat neurons was determined by quantitative real-time polymerase chain reaction (qRT-PCR). Regulatory effects of miRNA-324-5p on viability, and apoptosis of OGD-...
3 CitationsSource