Kai-Ru Song
Shenyang Pharmaceutical University
CytotoxicityBiological activityCytotoxic T cellGenusEnzymeChemistryApoptosisGlycosidePhytochemicalIn vitroIn vivoG1 phasePhenylpropanoidLeptopusHeLaEuphorbiaceaeMedicinal plantsNatural productAglyconeAnti-inflammatoryHemolysistert-Butyl hydroperoxideHydrolysateLeptopus chinensisDoxorubicin HydrochlorideCaesalpinia cucullataPentacyclic triterpenoidsOxidative injuryAnti inflammationBiosynthesisBiochemistryTraditional medicineMAPK/ERK pathwayStereochemistryProtein kinase BPharmacology
5Publications
3H-index
3Citations
Publications 5
Newest
#1Shizhou Qi (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Xinxin Zhang (SPU: Shenyang Pharmaceutical University)H-Index: 3
Last. Huiyuan Gao (SPU: Shenyang Pharmaceutical University)H-Index: 12
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Abstract Our present and previous phytochemical investigations on Leptopus lolonum have resulted in the isolation of almost 30 phenylpropanoid-conjugated pentacyclic triterpenoids (PCPTs). During the continuous study on PCPTs, this kind of triterpenoid ester is considered as a natural product with low toxicity because of it’s widely distribution in natural plants and edible fruits including kiwi fruit, durian, jujube, pawpaw, apple and pear. In the present work, we report the isolation, structur...
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#1Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
#2Yiren Yang (SPU: Shenyang Pharmaceutical University)H-Index: 4
Last. Huiyuan Gao (SPU: Shenyang Pharmaceutical University)H-Index: 12
view all 8 authors...
1 CitationsSource
#1Shizhou Qi (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Huiyuan Gao (SPU: Shenyang Pharmaceutical University)H-Index: 12
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Abstract Most of Euphorbiaceae plants are considered as folk medicinal plants because of their various pharmacological effects. However, there are eight Leptopus genus plants which belong to Euphorbiaceae have never be investigated. Thus, four Leptopus genus plants were collected to study their chemical constituents and pharmacological activities. In the present work, the cytotoxicities of the extracts of four Leptopus genus plants were evaluated before phytochemical experiments. And nine new ph...
1 CitationsSource
#1Liping LongH-Index: 3
Last. Huiyuan GaoH-Index: 12
view all 9 authors...
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#1Yiren Yang (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Liping Long (SPU: Shenyang Pharmaceutical University)H-Index: 3
Last. Luping Sha (SPU: Shenyang Pharmaceutical University)H-Index: 2
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Barrigenol-like triterpenoids (BATs) showed promising anti-tumor, anti-inflammatory and anti-Alzheimer's activities, while, the inhibitory strength was usually affected by their states with aglycones or glycosides. In order to find more BATs as new anti-tumor agents with much more efficiency, the chemical and pharmaceutical studies were carried out on the acid hydrolysate product (AHP) of Semen Aesculi crude extract. Thirteen BATs, including three new aglycones (1–3), two new glycosides (4, 5) a...
1 CitationsSource