Tyler Yan
University of British Columbia
Quality of lifeHerd immunitySleep in non-human animalsPsychiatryPhenotypePublic healthSurgeryCross-sectional studyMutantLogistic regressionOdds ratioCoagulation testingCathepsin DHEK 293 cellsIntensive care medicinePediatricsAdverse effectVentilation (architecture)VaccinationPsychological interventionPositive airway pressureFluoxetineLactobacillus rhamnosusFrontotemporal lobar degenerationWillingness to acceptGonadal veinMechanical ventilationAortic aneurysmMelatoninToddlerSaccharomyces boulardiiTest (assessment)Autism spectrum disorderSeal (mechanical)Depression (differential diagnoses)MEDLINEContinuous positive airway pressureDiarrheaAntibiotic-associated diarrheaVascular graftingMajor depressive disorderOvarian veinIntervention (counseling)Emergency departmentVaccination schedulePopulationRight Renal ArteryHematologic testingRight Common Iliac ArteryArterial reconstructionEar infectionRecurrent epistaxisGynecologyPositive pressure ventilationCoronavirus disease 2019 (COVID-19)Effective treatmentAdjunctive treatmentSafety profileInitial treatmentVein graftTime to effectNon invasiveAntibioticsCancer researchFamily medicineMolecular medicineHaploinsufficiencyMedicineBiologyPandemicNonsense mutation
12Publications
3H-index
51Citations
Publications 12
Newest
Question null Un enfant vient a ma clinique et se plaint d’une epistaxis recurrente, notamment de plusieurs episodes par annee depuis qu’il est tout petit. Les saignements de nez se produisent dans les 2 narines et durent souvent longtemps, sans qu’il y ait de tendances saisonnieres apparentes. Quelles sont les interventions sures et efficaces pour l’epistaxis chez les enfants, et chez quels patients des analyses hematologiques s’imposeraient-elles? null Reponse null L’epistaxis se produit chez ...
Source
Question null A child came to my clinic complaining of recurrent epistaxis with several episodes occurring every year since he was a toddler. The nosebleeds affect both nostrils, often lasting for an extended period of time and occurring in no apparent seasonal pattern. What interventions are safe and effective for recurrent epistaxis in children, and which patients warrant hematologic testing? null Answer null Epistaxis affects more than half of children by the time they are 10 years old, with ...
Source
#1Tyler Yan (UBC: University of British Columbia)H-Index: 3
#2Sally H.J. Choi (UBC: University of British Columbia)H-Index: 4
Last. Jerry C. Chen (UBC: University of British Columbia)
view all 3 authors...
Abstract We report a Case of a hybrid aortic debranching procedure for repair of a paravisceral inflammatory aortic aneurysm. Vein grafts were chosen over prosthetics due to concern for infection as a possible etiology. The gonadal vein was successfully used as a vein graft between the right common iliac artery and the right renal artery prior to aortic endograft placement.
Source
#1Ran D. Goldman (UBC: University of British Columbia)H-Index: 33
#2Tyler Yan (UBC: University of British Columbia)H-Index: 3
Last. Georg Staubli (Boston Children's Hospital)H-Index: 11
view all 23 authors...
Abstract Background More than 100 COVID-19 vaccine candidates are in development since the SARS-CoV-2 genetic sequence was published in January 2020. The uptake of a COVID-19 vaccine among children will be instrumental in limiting the spread of the disease as herd immunity may require vaccine coverage of up to 80% of the population. Prior history of pandemic vaccine coverage was as low as 40% among children in the United States during the 2009 H1N1 influenza pandemic. Purpose To investigate pred...
37 CitationsSource
#1Vionarica Gusti (UBC: University of British Columbia)H-Index: 1
#2Wan Jun Wu (UBC: University of British Columbia)
Last. Abhijit Pandhari (UBC: University of British Columbia)
view all 21 authors...
Goal: COSMIC Medical, a Vancouver-based open-source volunteer initiative, has designed an accessible, affordable, and aerosol-confining non-invasive positive-pressure ventilator (NIPPV) device, known as the COSMIC Bubble Helmet (CBH). This device is intended for COVID-19 patients with mild-to-moderate acute respiratory distress syndrome. System Design : CBH is composed of thermoplastic polyurethane, which creates a flexible neck seal and transparent hood. This device can be connected to wall oxy...
Source
#1Ran D. Goldman (UBC: University of British Columbia)H-Index: 33
#2Shashidhar R Marneni (Children's Medical Center of Dallas)H-Index: 3
view all 19 authors...
PURPOSE: This study determined the predictors of caregivers' willingness to accept an accelerated regulatory process for the development of vaccines against coronavirus disease 2019 (COVID-19). METHODS: An international cross-sectional survey was administered to 2557 caregivers of children in 17 pediatric emergency departments (EDs) across 6 countries from March 26, 2020, to June 30, 2020. Caregivers were asked to select 1 of 4 choices with which they most agreed regarding a proposed COVID-19 va...
14 CitationsSource
#1J. Frew (UBC: University of British Columbia)H-Index: 2
#1Jonathan Frew (UBC: University of British Columbia)H-Index: 1
Last. Haakon B. Nygaard (UBC: University of British Columbia)H-Index: 18
view all 17 authors...
BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a devastating and progressive disorder, and a common cause of early onset dementia. Progranulin (PGRN) haploinsufficiency due to autosomal dominant mutations in the progranulin gene (GRN) is an important cause of FTLD (FTLD-GRN), and nearly a quarter of these genetic cases are due to a nonsense mutation. Premature termination codons (PTC) can be therapeutically targeted by compounds allowing readthrough, and aminoglycoside antibiotics are k...
8 CitationsSource
Abstract Question I have several patients with autism spectrum disorder (ASD) who experience difficulties with sleep, affecting the quality of life of both the child and the family. Is melatonin an effective treatment for sleep problems in children with this condition? Answer Autism spectrum disorder is prevalent among children in Canada and globally, with most affected children experiencing troubles with sleep. Behavioural therapy is the first-line treatment for sleep problems in children with ...
Resume Question Un parent m’a recemment demande si son enfant devrait prendre des probiotiques pour reduire la possibilite d’une diarrhee pendant une antibiotherapie pour une infection de l’oreille. Les probiotiques sont-ils surs et efficaces pour prevenir la diarrhee liee aux antibiotiques et, dans l’affirmative, quelles sont les souches et les doses recommandees? Reponse Les 2 types de probiotiques recommandes pour prevenir la diarrhee associee aux antibiotiques chez l’enfant sont les Lactobac...
1 Citations
Abstract Question I recently had a parent ask me if their child should be taking probiotics to reduce the impending diarrhea while using antibiotic treatment for an ear infection. Are probiotics effective and safe in preventing antibiotic-associated diarrhea, and, if so, what strain and dose are recommended? Answer The 2 types of probiotics recommended to prevent pediatric antibiotic-associated diarrhea are Lactobacillus rhamnosus GG and Saccharomyces boulardii. Although an optimal dose has yet ...
1 Citations