Binglin Li
Southern Medical University
Self-healing hydrogelsTransforming growth factorBiomedical engineeringNanomaterialsNanoparticleChemistryApoptosisMaterials scienceBacterial cell structureHeat shock proteinIn vivoCombinatorial chemistryHalloysiteBiocompatibilityDextranHyaluronic acidNanotubeOsteosarcomaMicrowave ablationCopper sulfideHemostasisPeptideChitosanOxideWound healingFibroblastAngiogenesisOncogeneCell cycleBone regenerationGrapheneChemical engineeringAntimicrobialCancer researchNanosheetBacteriaAntimicrobial peptidesAdhesiveMicrobiologyScaffoldNanocomposite
Publications 5
#1Zhan Li (Southern Medical University)
#2Binglin Li (Southern Medical University)H-Index: 3
Last. Ying Zhang (Southern Medical University)H-Index: 1
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Abstract A series of halloysite nanotube (HNT)-doped chitosan (CS)/oxidized dextran (ODEX) adhesive hydrogels were developed through a Schiff base reaction. The resultant CS/ODEX/HNT hydrogels could not only form in situ on wounds within only 1 s when injected, but could also adapt to wounds of different shapes and depths after injection. We established four rat and rabbit hemorrhage models and demonstrated that the hydrogels are better than the clinically used gelatin sponge for reducing hemost...
#1Tingting Wu (JNU: Jinan University)H-Index: 8
#2Binglin Li (Southern Medical University)H-Index: 3
Last. Tao ZhangH-Index: 4
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The strontium substituted hydroxyapatite (SrHA) is a commonly used material in bone regeneration for its good osteoconductive and high alkaline phosphatase (ALP) activity. However, the SrHA nanoparticles dropped scaffolds cannot properly fit the required mechanical properties. Here, we used facile hydrothermal method to synthesize graphene oxide (GO) reinforced SrHA nanoparticles. The scaffold was fabricated using freeze drying method by incorporating SrHA/GO nanoparticles into chitosan (CS) and...
2 CitationsSource
#1Wanshun Wang (Guangzhou University of Chinese Medicine)H-Index: 4
#1Wanshun Wang (Guangzhou University of Chinese Medicine)H-Index: 1
Last. Yao Lu (Southern Medical University)H-Index: 14
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Antibacterial nanomaterials have attracted growing interest for bacterial infection therapy. However, most nanomaterials eliminate bacteria either physically or chemically, which hampers their efficacy when dealing with multidrug-resistant bacteria. To overcome this, we integrated copper sulfide (CuS) nanoparticles with active graphene oxide nanosheets (GO NSs) to synthesize a superior nanocomposite (CuS/GO NC) that acts both physically and chemically on the bacteria. CuS/GO NC was produced usin...
7 CitationsSource
#1Lingling Chen (Southern Medical University)H-Index: 7
#2Ming Wang (Southern Medical University)H-Index: 13
Last. Qingshui Yin (Southern Medical University)H-Index: 11
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Osteosarcoma is the most common malignant bone tumour and the second leading cause of cancer‑related death in children and adolescents. Microwave ablation has an excellent therapeutic effect on bone tumours by instantaneously increasing the temperature in the tumour; however, there is a risk of damaging the surrounding healthy tissues by exposure to a high temperature when the treatment power is too large. In the present study, two anti‑tumour reagents, a heat shock protein 90 (HSP90) inhibitor ...
2 CitationsSource
Abstract The increase in severe infections caused by antibiotic drug resistance and the decrease in the number of new antibacterial drugs approved for use in the last few decades are driving the need for the development of new antimicrobial strategies. Antimicrobial peptides (AMPs) are a potential new class of antimicrobial drugs that are expected to solve the problem of global antibiotic drug resistance. Herein, the AMP Tet213 was immobilised onto the substrates of alginate (ALG), hyaluronic ac...
23 CitationsSource