Mengxi Shen
Tianjin Medical University General Hospital
Study heterogeneityPhosphorylationDownregulation and upregulationAMPA receptorRandomized controlled trialReceptorChemistryPhysical therapySubgroup analysisWestern blotCochrane LibraryNeuropathic painNerve blockSalinePostherpetic neuralgiaRemifentanilHyperalgesiaInterventional pain managementArteminPhosphorylation InhibitionIncisional painReceptor complexTail veinThreshold of painAnesthesiaPeripheralMedicineMeta-analysisPharmacology
3Publications
2H-index
5Citations
Publications 4
Newest
#1Mengxi Shen (Tianjin Medical University General Hospital)H-Index: 2
#2Naqi Lian (Tianjin Medical University General Hospital)H-Index: 4
Last. Yonghao Yu (Tianjin Medical University General Hospital)H-Index: 24
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#1Peng Liu (Tianjin Medical University General Hospital)H-Index: 1
#2Chengcheng Song (Tianjin Medical University General Hospital)H-Index: 3
Last. Linlin Zhang (Tianjin Medical University General Hospital)H-Index: 8
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Abstract Introduction Synaptosomal associated proteins of 25 kDa (SNAP-25), as a member of stable soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex, is critical for membrane fusion and required for the release of neurotransmitters. The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor is implicated in pathologic pain. This study aimed to investigate whether and how SNAP-25 regulated AMPA receptors in neuropathic pain. Methods Male Sprague–Dawley rat...
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#1Suqian Guo (Tianjin Medical University General Hospital)H-Index: 5
#2Mengxi Shen (Tianjin Medical University General Hospital)H-Index: 2
Last. Guolin Wang (Tianjin Medical University General Hospital)H-Index: 21
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Background: Herpes zoster (HZ) is identified to induce postherpetic neuralgia (PHN) which is difficult to cure. PHN-related pain brings patients not only physical discomfort but also mental depression and anxiety. Currently, the main purpose of PHN treatment is to reduce patients' pain. Now treatment combining some international pain management and drug therapy has come up. Aims and Objective: This study aims to evaluate the effect of interventional management through meta-analysis. Materials an...
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#1Lin Su (Tianjin Medical University General Hospital)H-Index: 4
#2Ruichen Shu (Tianjin Medical University General Hospital)H-Index: 7
Last. Guolin Wang (Tianjin Medical University General Hospital)H-Index: 21
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Objective To evaluate the changes in the expression of artemin in skin around the incision during remifentanil-induced hyperalgesia in the rats with incisional pain. Methods Thirty-two healthy male Sprague-Dawley rats, aged 10-12 weeks, weighing 250-280 g, were divided into 4 groups (n=8 each) using a random number table: control group (group C), incisional pain group (group I), remifentanil group (group R) and incisional pain plus remifentanil group (group I+ R). Remifentanil was intravenously ...
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