Ketevani Kankava
Tbilisi State Medical University
Internal medicineEndocrinologyPathologyOncologyPediatricsHuman leukocyte antigenImmunohistochemistryYoung adultHazard ratioImmunotherapyKi-67Large cellMEDLINELymphContext (language use)Differential diagnosisLymph nodeCD44AdenocarcinomaKRASMitotic CountProliferation indexNeuroendocrine CarcinomasMolecular analysisAdult agePrognostic factorGene mutationGastro entero pancreaticLabeling indexMesenteric tumorPersonalized treatmentNomogramConfidence intervalProportional hazards modelHistologyMedicineBiologyImmune systemGastroenterology
Publications 12
#1Ketevani Kankava (Tbilisi State Medical University)H-Index: 3
#2Kvaratskhelia E (Tbilisi State Medical University)H-Index: 3
Last. E. Abzianidze (Tbilisi State Medical University)H-Index: 4
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The role of epigenetics in tumor development and progression is actively being studied. The aim of our current pilot study is to analyze correlation of changes in the levels of methyltransferases in nuclear extracts of blood cells with some morphological and phenotypic characteristics of breast cancer. The levels of DNMT1, DNMT3a and H3K4 methyltransferase were measured. The results showed that the level of DNMT1 was highest in the control group but correlation with the tumor grade was just mode...
#1E. AbzianidzeH-Index: 4
#2Kvaratskhelia EH-Index: 3
Last. Merab G. TsagareliH-Index: 11
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: Acute pain is associated with tissue damage, which results in the release of inflammatory mediators. Recent studies point to the involvement of epigenetic mechanisms (DNA methylation) in the development of pain. We have found that during acute inflammatory pain induced by the application of 10% mustard oil on the tongues of rats, levels of DNMT3a and 3b were elevated markedly (36 and 42 % respectively), whereas the level of DNMT1 was not changed significantly. Previous injection of Xefocam wit...
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