Claudia Vater
University of Vienna
Penetration (firestop)CytotoxicityCorneocyteChemistryBiocompatibilityHuman skinCurcuminStratum corneumSodium laureth sulfateSodium dodecyl sulfatePhospholipidLecithinUreaChromatographyPermeationViability assayPulmonary surfactantZeta potentialTransepidermal water loss
Publications 3
#1Claudia VaterH-Index: 2
Last. Victoria KlangH-Index: 14
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(1) Background: The aim of the study was to evaluate the effect of pure lecithins in comparison to a conventional surfactant on skin in vivo. (2) Methods: Physiological skin parameters were evaluated at the beginning and the end of the study (day 1 and day 4) (n = 8, healthy forearm skin) with an Aquaflux®, skin-pH-Meter, Corneometer® and an Epsilon® sensor. Confocal Raman spectroscopy was employed to monitor natural moisturizing factor, urea and water content of the participants’ skin. Tape str...
#1Claudia Vater (University of Vienna)H-Index: 2
#2Victoria Hlawaty (University of Vienna)H-Index: 1
Last. Claudia Valenta (University of Vienna)H-Index: 34
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Abstract Surfactants are important ingredients in pharmaceutical and cosmetic formulations, as in creams, shampoos or shower gels. As conventional emulsifiers such as sodium dodecyl sulfate (SDS) have fallen into disrepute due to their skin irritation potential, the naturally occurring lecithins are being investigated as a potential alternative. Thus, lecithin-based nanoemulsions with and without the drug curcumin, known for its wound healing properties, were produced and characterised in terms ...
7 CitationsSource
#1Claudia Vater (University of Vienna)H-Index: 2
#2Anja Adamovic (University of Vienna)H-Index: 1
Last. Claudia Valenta (University of Vienna)H-Index: 34
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Abstract As constituents of cellular membranes, lecithins feature high biocompatibility and great emulsifying properties due to their amphiphilicity. Additionally, there are expectations that these naturally occurring emulsifying agents can replace other skin damaging emulsifiers like sodium dodecyl sulfate or sodium laureth sulfate. However, cytotoxicity data of lecithin-based formulations on primary human skin cells are scarce. Thus, we developed nanoemulsions with different kinds of surfactan...
12 CitationsSource