S. Tomatis
Imaging phantomDosimeterOpticsPhysicsInternal medicineRadiologyBiomedical engineeringSurgeryPathologyOncologyTransmittanceAbsorbed doseArtificial intelligenceMultispectral imageMaterials scienceMedical physicsChemotherapyMelanomaSoftwareNasopharyngeal carcinomaGel dosimetryLesionNuclear medicineFricke gelComputer scienceRadiation therapyDose profileMedicineDosimetry
Publications 37
#1Ester OrlandiH-Index: 22
#2S. TomatisH-Index: 13
Last. Carlo FallaiH-Index: 21
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Aim: To analyze the patterns of locoregional failure following intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) at our institution, as part of an internal quality assurance program. We aimed to investigate the potential existence of a correlation between any part of the IMRT process and clinical outcome. Methods & materials: A total of 106 non-metastatic NPC patients consecutively treated with IMRT (with or without chemotherapy) were analyzed. Radiotherapy was administe...
22 CitationsSource
#1S. TomatisH-Index: 13
#2Tiziana RancatiH-Index: 27
Last. Riccardo ValdagniH-Index: 51
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The aim of this study was to develop a model exploiting artificial neural networks (ANNs) to correlate dosimetric and clinical variables with late rectal bleeding in prostate cancer patients undergoing radical radiotherapy and to compare the ANN results with those of a standard logistic regression (LR) analysis. 718 men included in the AIROPROS 0102 trial were analyzed. This multicenter protocol was characterized by the prospective evaluation of rectal toxicity, with a minimum follow-up of 36 mo...
34 CitationsSource
#1Giovanni Naldi (University of Milan)H-Index: 16
Last. S. TomatisH-Index: 13
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Radiotherapeutic treatment of cancer is best conducted if the prescription dose is given to the tumor while surrounding normal tissues are maximally spared. With the aim to meet these requirements the complexity of radiotherapy techniques have steadily increased under a strong technological impulse, especially in the last decades. One problem involves the rate of the particular disposition of the structures of interest in a patient. Recently the authors (Tomatis et al., 2010; 2011) have proposed...
Abstract Radiation doses delivered to the patient during high dose rate brachytherapy treatments are susceptible to many inaccuracies and may not accurately match the planned doses. Novel Fricke gel dosimetric catheters (FGDC) were developed in the laboratory to be used for in vivo measurements of high dose rate brachytherapy treatments and represent possible tools to increase treatment accuracy. In this study, the dosimetric compound adopted to achieve FGDC was studied in terms of dose sensitiv...
3 CitationsSource
#1S. TomatisH-Index: 13
#2Mauro CarraraH-Index: 16
Last. R. Marchesini (University of Milan)H-Index: 13
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The purpose of the study was to develop a general method able to quantify the mutual disposition in the 3D space of critical organs with respect to the target when these structures are designed for a radiotherapy treatment plan. To that end, we introduce the "expansion intersection histogram", a function defined as the intersection between an organ at risk and the target volume, while the target is expanded in 3D.A software was developed to calculate the expansion intersection histogram of anato...
2 CitationsSource
#1Grazia GambariniH-Index: 16
#2Mauro CarraraH-Index: 16
Last. G. Battistoni (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 1
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Fricke-gel layer dosimeters (FGLDs) have shown promising features for attaining absolute measurements of the spatial distribution of the absorbed dose in radiotherapy. Good precision of results (within 3%) is achieved by means of calibration of each single dosimeter before measurement. The calibration is performed irradiating the dosimeter at a uniform and precisely known dose, in order to get a calibration matrix that must be used, with pixel-to-pixel manipulation, to obtain the dose image. A s...
5 CitationsSource
#1Mauro PalazziH-Index: 11
#2Daniela Alterio (IEO: European Institute of Oncology)H-Index: 21
Last. S. TomatisH-Index: 13
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Aims and background. Our previous survey showed that the patterns of postopera tive radiotherapy (PORT) for head and neck cancer (HNC) in Italy might be subopti mal. A prospective observational study was therefore designed to evaluate this issue in greater detail. Methods. All radiotherapy centers involved in the HNCWorking Group of the Italian Radiation Oncology Association were asked to enter into the study all patients treat ed with PORT during a 6-month period.
2 CitationsSource
1 CitationsSource
4 CitationsSource