Fabio Gionfra
Estrogen receptor alphaCaveolin 1Caveolin 2CaveolaeScaffold proteinSignal transductionEstrogen receptorTranscription factorBiologyCell biology
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#1Pierangela TottaH-Index: 16
#2Fabio GionfraH-Index: 1
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The sex hormone 17β-estradiol (E2) exerts pleiotropic effects by binding to the ligand-activated transcription factor estrogen receptor α (ERα). The E2:ERα complex regulates several physiological processes, including cell survival and proliferation, through transcriptional effects (i.e., estrogen responsive element [ERE]-based gene transcription) and non-transcriptional membrane-initiated effects (i.e., the activation of extra-nuclear signaling cascades), which derive from the activation of the ...
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