María L. Del Prado-Audelo
Monterrey Institute of Technology and Higher Education
Self-healing hydrogelsBiomedical engineeringNanoparticleNanotechnologyIntensive care medicineChemistryExtracellular matrixMaterials scienceIn vivoNeurodegenerationBiocompatibilityHyaluronic acidCurcuminSwellingChitosanDrug deliveryPolyvinylpyrrolidoneXanthan gumWound healingDrug releaseFood scienceChemical engineeringTissue engineeringPolymerThermogravimetric analysisPolyphenolMedicineBiologyImmune systemScaffoldPharmacology
23Publications
7H-index
137Citations
Publications 22
Newest
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion formation methods and to preserve the stability of carriers in liquid media. The deposition of non-ionic surfactants at the interface allows a considerable reduction of the globule of the emulsion with high biocompatibility and the possibility of oscillating the final sizes in a wide nanometric range. Therefore, this review presents an analysis of the three principal non-ionic surfactants utilized in the manufact...
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#1María L. Del Prado-Audelo (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 7
#2Isaac H. Caballero-Florán (IPN: Instituto Politécnico Nacional)H-Index: 5
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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The research of self-healable polymers intended for medical use has increased in the last 20 years. These materials can self-repair and recover their functionality after damage; thus, they are of significant interest in diverse academic areas, including the biomedical field. In this regard, numerous synthetic and natural polymers are being used to develop self-healing hydrogels for tissue engineering applications, particularly for the restoration of bones, cartilage, skin, and even the central n...
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Nanoparticles possess a huge potential to be employed in numerous biomedical purposes; their applications may include drug delivery systems, gene therapy, and tissue engineering. However, the in vivo use in biomedical applications requires that nanoparticles exhibit sterility. Thus, diverse sterilization techniques have been developed to remove or destroy microbial contamination. The main sterilization methods include sterile filtration, autoclaving, ionizing radiation, and nonionizing radiation...
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#1Bahare Salehi (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 38
#2Cristina Quispe (Arturo Prat University)H-Index: 15
Last. Wissam Zam (International University, Cambodia)H-Index: 1
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Oxidative stress is the imbalance between reactive oxygen species (ROS) production, and accumulation and the ability of a biological system to clear these reactive products. This imbalance leads to cell and tissue damage causing several disorders in human body, such as neurodegeneration, metabolic problems, cardiovascular diseases, and cancer. Cucurbitaceae family consists of about 100 genera and 1,000 species of plants including mostly tropical, annual or perennial, monoecious, and dioecious he...
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#1Gitishree DasH-Index: 17
#2Han-Seung ShinH-Index: 28
Last. Jayanta Kumar PatraH-Index: 32
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In recent decades, interest in the Cordyceps genus has amplified due to its immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents have been related with cytokine production such as interleukin (IL)-1β, IL-2, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor (TNF)-α, phagocytosis stimulation of immune cells, nitric oxide production by increasing inducible nitric oxide synthase activity, and stimulation of inflammatory response via mitogen-activated protein kin...
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#1Analizet Villar-Padilla (UNAM: National Autonomous University of Mexico)
#2María L. Del Prado-Audelo (UNAM: National Autonomous University of Mexico)H-Index: 7
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Bacterial vaginosis is a vaginal infection that affects 60% of women of reproductive age worldwide. It is mainly caused by the bacterium Gardnerella vaginalis and is a factor that increases the probability of getting sexually transmitted diseases. We aimed to develop a new pharmaceutical form for the treatment of vaginal infections. We employed the solving-casting method to fabricate a polymeric film with Xanthan gum, a natural polymer produced by the bacterium Xanthomonas campestris, and metron...
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#1Fernanda Kamila Godoy-Alvarez (UNAM: National Autonomous University of Mexico)
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Hyaluronic acid (HA) is one of the most attractive natural polymers employed in biomaterials with biological applications. This polysaccharide is found in different tissues of the body because it is a natural component of the extracellular matrix; furthermore, it has crucial functions in cell growth, migration, and differentiation. Since its biological characteristics, HA has been utilized for the new biomaterial’s development for tissue engineering, such as hydrogels. These hydrophilic macromol...
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#1Hernán CortésH-Index: 10
#2Octavio D. Reyes-Hernández (UNAM: National Autonomous University of Mexico)H-Index: 6
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Parkinson’s disease (PD) is one of the most prevalent neurodegenerative disorders worldwide. It is caused by the degeneration of dopaminergic neurons from the substantia nigra pars compacta. This neuronal loss causes the dopamine deficiency that leads to a series of functional changes within the basal ganglia, producing motor control abnormalities. L-DOPA is considered the gold standard for PD treatment, and it may alleviate its clinical manifestations for some time. However, its prolonged admin...
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#1Casandra Marilú Robles-Kanafany (UNAM: National Autonomous University of Mexico)
#2María L. Del Prado-Audelo (UNAM: National Autonomous University of Mexico)H-Index: 7
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Periodontal pain is a public health problem derived from different conditions, including periodontal diseases, prosthetic complications, and even extractions performed by dentist. There are various treatments to control acute dental pain, being the administration of analgesics, such as Lysine Clonixinate (LC), a common practice. Unfortunately, higher and repeated dosages are usually required. The purpose of this work was to develop a prolonged release pharmaceutical form as an alternative treatm...
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#1Tania López-Huante (UNAM: National Autonomous University of Mexico)
#2María L. Del Prado-Audelo (UNAM: National Autonomous University of Mexico)H-Index: 7
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Xanthan gum (XG) and polyvinylpyrrolidone (PVP) are two polymers with low toxicity, high biocompatibility, biodegradability, and high hydrophilicity, making them promising candidates for multiple medical aspects. The present work aimed to synthesize a hydrogel from a mixture of XG and PVP and crosslinked by gamma irradiation. We assessed the hydrogel through a series of physicochemical (FT-IR, TGA, SEM, and percentage of swelling) and biological (stability of the hydrogel in cell culture medium)...
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