Alejandro Szmulewicz
Harvard University
PsychiatryInternal medicinePsychosocialPsychologyRetrospective cohort studyCognitionNeurocognitivePediatricsCohort studyHazard ratioBipolar disorderAntipsychoticMoodProportional hazards modelMedicine
14Publications
12H-index
58Citations
Publications 38
Newest
#1Alejandro Szmulewicz (Harvard University)H-Index: 12
#2Brian T. Bateman (Brigham and Women's Hospital)H-Index: 65
Last. Krista F. Huybrechts (Brigham and Women's Hospital)H-Index: 53
view all 4 authors...
The US FDA issued a black-box warning against co-prescription of antipsychotic (AP) agents and opioids due to the risk of respiratory depression, but evidence on the comparative safety of sedating vs nonsedating APs is lacking. We classified APs as sedating (eg, quetiapine, olanzapine, and chlorpromazine) and nonsedating (eg, aripiprazole, haloperidol, and risperidone) based on their affinity to the histamine-1 neuroreceptor (Ki < or ≥20, respectively) and sought to compare the rate of overdose ...
Source
#1Emily Kline (Harvard University)H-Index: 17
#2Kelsey A. Johnson (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
Last. Margaret Guyer (Massachusetts Department of Mental Health)H-Index: 6
view all 11 authors...
AIM Increasing evidence points to the value of coordinated specialty care (CSC) for early intervention in psychotic disorders. This report characterizes clinical and socio-demographic features of patients at CSC programs in Massachusetts (MA), assessed by a standardized battery incorporated into "real-world" clinical care. METHODS The MA psychosis network for early treatment developed a pilot battery to coordinate assessments across six CSC clinics. Programs reported baseline, 6-month, and 12-mo...
Source
#1Marina P. Valerio (CONICET: National Scientific and Technical Research Council)H-Index: 9
#2Alejandro Szmulewicz (UBA: University of Buenos Aires)H-Index: 12
Last. Diego J. Martino (Favaloro University)H-Index: 21
view all 4 authors...
Source
#2Dost ÖngürH-Index: 62
Last. John HsuH-Index: 41
view all 9 authors...
Objective: A central objective of early psychosis therapy is to restore social functioning (e.g., through employment and education). Employment and educational outcomes during the COVID-19 pandemic...
Source
#1Alejandro Szmulewicz (Harvard University)H-Index: 12
#2Brian T. Bateman (Brigham and Women's Hospital)H-Index: 65
Last. Krista F. HuybrechtsH-Index: 53
view all 4 authors...
Objective: The Z-drugs (zolpidem, zopiclone, zaleplon) are widely used to treat insomnia in patients receiving prescription opioids, and the risk of overdose resulting from this coprescription has ...
Source
#1Augusto FerrarisH-Index: 4
#2Belén BlascoH-Index: 1
Last. Alejandro Szmulewicz (Harvard University)H-Index: 12
view all 7 authors...
OBJECTIVE Mounting evidence suggests that antipsychotics may have immunomodulatory effects, but their impact on disseminated infections remains unknown. This study thus sought to estimate the effect of antipsychotic treatment on the occurrence of bloodstream infection during long-term follow-up in adult patients with chronic obstructive pulmonary disease. METHODS This retrospective cohort study, with new user and active comparator design, included adult patients seen from January 2008 to June 20...
Source
#1Kaisla Komulainen (UH: University of Helsinki)H-Index: 3
#2Kia Gluschkoff (UH: University of Helsinki)H-Index: 9
Last. Markus Jokela (UH: University of Helsinki)H-Index: 78
view all 6 authors...
Objectives Many older adults with depression do not receive adequate treatment. Differences in treatment utilization may reflect the heterogeneous nature of depression, encompassing multiple distinct symptoms. We assessed whether depressive symptoms are differentially associated with subsequent health care utilization with respect to three outcomes as follows: (1) contact with a medical doctor (MD), (2) depression-specific treatment, and (3) inpatient psychiatric admission. Methods/design Longit...
Source
#2Marina P. Valerio (CONICET: National Scientific and Technical Research Council)H-Index: 9
Last. Diego J. Martino (CONICET: National Scientific and Technical Research Council)H-Index: 21
view all 4 authors...
OBJECTIVE In this study, we aimed to evaluate the role of cognitive performance and measures of clinical course - including both syndromal and subsyndromal symptomatology- as determinants of the functional outcome of patients with Bipolar Disorder (BD) during a mean follow-up period of more than 4 years. METHODS Seventy patients with euthymic BD completed a neurocognitive battery at study entry. Clinical course was assessed prospectively for a period longer than 48 months by two measures: time s...
Source
#1Augusto Ferraris (Ariès)H-Index: 1
#2Federico Angriman (U of T: University of Toronto)H-Index: 10
Last. Alejandro Szmulewicz (Harvard University)H-Index: 12
view all 3 authors...
Source
#1Alejandro Szmulewicz (Harvard University)H-Index: 12
#2Nicole M. Benson (Harvard University)H-Index: 7
Last. Dost Öngür (Harvard University)H-Index: 62
view all 5 authors...
Aim To evaluate the impact of the COVID-19 pandemic on clinical outcomes, we used data from Electronic Health Records from 128 patients receiving care at a First Episode Psychosis clinic. Methods Rates of admission or emergency room (ER) visits from January 2020 to July 2020 were analysed using difference-in-difference regression. We used the same weeks in 2019 to control for seasonality. Results We found 17 hospitalizations or ER visits between 1 January 2020 and 13 March 2020 (incidence rate: ...
Source
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.