Peng Lin
Boston University
Bessel functionSignalOpticsPhysicsAchromatic lensComputer graphics (images)Biomedical engineeringDeformable mirrorMicroscopyAugmented realityTomographyRaman scatteringChemistryScatteringMaterials scienceOptical fiberVirtual realityLens (optics)Image resolutionIn vivoBessel beamStimulated ramanRaman spectroscopyHorizontal scan rateComputer scienceOptoelectronicsCladding (fiber optics)Chemical imagingMicroscopeRGB color model
20Publications
6H-index
135Citations
Publications 19
Newest
#1Peng Lin (BU: Boston University)H-Index: 6
#2Hongli Ni (BU: Boston University)H-Index: 1
Last. Ji-Xin Cheng (BU: Boston University)H-Index: 83
view all 7 authors...
Stimulated Raman scattering (SRS) microscopy enables the imaging of molecular events on a human subject in vivo, such as filtration of topical drugs through the skin and intraoperative cancer detection. A typical approach for volumetric SRS imaging is through piezo scanning of an objective lens, which often disturbs the sample and offers a low axial scan rate. To address these challenges, we have developed a deformable mirror-based remote-focusing SRS microscope, which not only enables high-qual...
Source
#1Xinyu Wang (Xidian University)H-Index: 2
#2Lin WangH-Index: 3
Last. Xueli Chen (Xidian University)H-Index: 17
view all 8 authors...
Stimulated Raman scattering (SRS) microscopy has the ability of noninvasive imaging of specific chemical bonds and been increasingly used in biomedicine in recent years. Two pulsed Gaussian beams a...
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#1Cheng Zong (BU: Boston University)H-Index: 18
#2Chi Zhang (BU: Boston University)H-Index: 20
Last. Ji-Xin Cheng (BU: Boston University)H-Index: 83
view all 8 authors...
Traditional electrochemical measurements based on either current or potential responses only present the average contribution of an entire electrode's surface. Here, we present an electrochemical photothermal reflectance microscope (EPRM) in which a potential-dependent nonlinear photothermal signal is exploited to map an electrochemical process with sub-micron spatial resolution. By using EPRM, we are able to monitor the photothermal signal of a Pt electrode during the electrochemical reaction a...
1 CitationsSource
#1Zhaoyi Li (Harvard University)H-Index: 7
#2Peng Lin (BU: Boston University)H-Index: 6
Last. Federico Capasso (Harvard University)H-Index: 146
view all 9 authors...
Virtual and augmented realities are rapidly developing technologies, but their large-scale penetration will require lightweight optical components with small aberrations. We demonstrate millimeter-scale diameter, high-NA, submicron-thin, metasurface-based lenses that achieve diffraction-limited achromatic focusing of the primary colors by exploiting constructive interference of light from multiple zones and dispersion engineering. To illustrate the potential of this approach, we demonstrate a vi...
3 CitationsSource
#1Peng Lin (BU: Boston University)H-Index: 6
#2Hongli Ni (BU: Boston University)H-Index: 1
Last. Ji-Xin Cheng (BU: Boston University)H-Index: 83
view all 8 authors...
Operable under ambient light and providing chemical selectivity, stimulated Raman scattering (SRS) microscopy opens a new window for imaging molecular events on a human subject, such as filtration of topical drugs through the skin. A typical approach for volumetric SRS imaging is through piezo scanning of an objective lens, which often disturbs the sample and offers a low axial scan rate. To address these challenges, we have developed a deformable mirror-based remote-focusing SRS microscope, whi...
2 CitationsSource
#1Zhaoyi Li (Harvard University)H-Index: 7
#2Peng Lin (BU: Boston University)H-Index: 6
Last. Federico Capasso (Harvard University)H-Index: 146
view all 8 authors...
Source
#1Xueli ChenH-Index: 17
#2Xinyu WangH-Index: 2
Last. Ji-Xin Cheng (BU: Boston University)H-Index: 83
view all 6 authors...
Scattering is a huge challenge for microscopic imaging. Indeed, it is difficult to observe target chemicals in scattering media by means of the current Gaussian beam-based stimulated Raman scattering (SRS) microscopy, since the tight focus of the Gaussian beam is destroyed after propagating through a certain distance. Bessel beams, featuring self-reconstructing property, may bring a solution to this problem. By combining Bessel beams with SRS microscopy, we can probe the SRS signal from a scatte...
1 CitationsSource
#1Zhaoyi Li (Harvard University)H-Index: 7
#2Peng Lin (BU: Boston University)H-Index: 6
Last. Federico Capasso (Harvard University)H-Index: 146
view all 8 authors...
We demonstrated a large and RGB-achromatic metalens by novel design methods. Furthermore, we realized a compact platform for a virtual reality / augmented reality system based on an RGB metalens and a fiber scanning display.
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#1Xueli Chen (Xidian University)H-Index: 17
#2Shouping Zhu (Xidian University)H-Index: 21
Last. Jie Tian (CAS: Chinese Academy of Sciences)H-Index: 95
view all 11 authors...
Objective: Stimulated Raman projection tomography (SRPT), a recently developed label-free volumetric chemical imaging technology, has been reported to quantitatively reconstruct the distribution of chemicals in a three-dimensional (3D) complex system. The current image reconstruction scheme used in SRPT is based on a filtered back projection (FBP) algorithm that requires at least 180 angular-dependent projections to rebuild a reasonable SRPT image, resulting in a long total acquisition time. Thi...
1 CitationsSource
#1Jiayingzi Wu (BU: Boston University)H-Index: 2
#2Hyeon Jeong Lee (BU: Boston University)H-Index: 10
Last. Ji-Xin Cheng (BU: Boston University)H-Index: 83
view all 11 authors...
Development of molecular probes holds great promise for early diagnosis of aggressive prostate cancer. Here, 2-[3-(1,3-dicarboxypropyl) ureido] pentanedioic acid (DUPA)-conjugated ligand and bis-isoindigo-based polymer (BTII) are synthesized to formulate semiconducting polymer nanoparticles (BTII-DUPA SPN) as a prostate-specific membrane antigen (PSMA)-targeted probe for prostate cancer imaging in the NIR-II window. Insights into the interaction of the imaging probes with the biological targets ...
11 CitationsSource