Hao Pan
Guangzhou University of Chinese Medicine
PhosphorylationCancerCaspase 1CellPyroptosisChemistryMesenchymal stem cellInflammationArthritisWedelolactoneInflammasomePaclitaxelGlycyrrhiza uralensisHedyotis diffusaAtractylodes lanceaCurcuma zedoariaMir 181a 5pChondrogenesisSecretionCancer researchBreast cancerCell growthMedicineCell biology
Publications 3
#1Shanyu YeH-Index: 3
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#1Hao Pan (Guangzhou University of Chinese Medicine)H-Index: 2
#2Yuqing Lin (Guangzhou University of Chinese Medicine)H-Index: 1
Last. Dongfeng Chen (Guangzhou University of Chinese Medicine)H-Index: 22
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OBJECTIVES Wedelolactone exhibits regulatory effects on some inflammatory diseases. However, the anti-inflammatory mechanism of wedelolactone has not been entirely unravelled. Therefore, the present study focuses on investigating the mechanism of wedelolactone on NLRP3 inflammasome in macrophages and its influence on MSU-induced inflammation. MATERIALS AND METHODS BMDM, J774A.1 and PMA-differentiated THP-1 macrophages were primed with LPS and then stimulated with ATP or nigericin or MSU crystal ...
10 CitationsSource
#1Neng Wang (Guangzhou University of Chinese Medicine)H-Index: 4
#2Bowen Yang (Guangzhou University of Chinese Medicine)H-Index: 9
Last. Fengxue Zhang (Guangzhou University of Chinese Medicine)H-Index: 11
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Chinese formulas have been paid increasing attention in cancer multidisciplinary therapy due to their multi-targets and multi-substances property. Here, we aim to investigate the anti-breast cancer and chemosensitizing function of Ai Du Qing (ADQ) formula made up of Hedyotis diffusa, Curcuma zedoaria (Christm.) Rosc., Astragalus membranaceus (Fisch.) Bunge and Glycyrrhiza uralensis Fisch. Our findings revealed that ADQ significantly inhibited cell proliferation in both parental and chemo-resista...
13 CitationsSource