Mengjie Sun
Ocean University of China
PolysaccharideHistamine H1 receptorSelf-healing hydrogelsHistamineUltimate tensile strengthNanomaterialsNuclear chemistrySolubilityNanoparticleBiodegradationMolar mass distributionHistamine receptorControlled releaseNanotechnologyTranscellularIntensive care medicineShrinkageBioavailabilityNanocarriersAqueous solutionLiposomeChemistryParticle sizeLower critical solution temperatureMaterials scienceCrystallizationRaw materialAllergyPsychological interventionAsthmaDemineralizationAntagonistLysozymeOral administrationIrritationBiocompatibilityPortunus trituberculatusSelf-healingCurcuminBiopolymerCetirizineChitosanDrug deliveryAntibacterial activityUreaKetotifenVinyl alcoholDeoxycholic acidIntestinal permeabilityIntestinal epitheliumDrug accumulationCancer therapyDelivery systemBiological propertyDrug release rateElectrostatic adsorptionWound dressingPolymer coatingDemand marketSelf assembledOral retinoidMechanical propertyOral routeWound managementAllergen avoidanceDrug releaseComputer scienceChemical engineeringTissue engineeringPharmacotherapyCancer researchColorectal cancerMucous membrane of noseParacellular transportMedicineDosage formNasal administrationImmune systemNanofiberPharmacologyToughness
Publications 12
#1Mengjie Sun (Ocean University of China)H-Index: 6
#2Xiaoping YuH-Index: 6
Last. Xiguang Chen (Ocean University of China)H-Index: 61
view all 6 authors...
Abstract Allergic rhinitis (AR) was a chronic airway inflammatory disease. Nasal administration showed superiorities due to its effective drug absorption. Cetirizine (CTZ) was a common H 1 -antihistamine in allergic disorders therapy, while hydrophobicity and irritation to nasal mucosa limited its application. In this regard, deoxycholate-chitosan-hydroxybutyl nanoparticles with CTZ covalently grafted and free CTZ encapsulated (CTZ:CDHBCs-NPs) were synthesized as nasal adaptive nano-drug deliver...
5 CitationsSource
#1Meiping Tian (Ocean University of China)H-Index: 6
#2Rui-Xi Song (Ocean University of China)H-Index: 1
Last. Xiguang Chen (Ocean University of China)H-Index: 61
view all 6 authors...
Abstract Liposomes (LPs), a delivery vehicle for stabilizing drugs, the characteristics of being easy to aggregate and fuse limit its application. Polymer coating is a promising way to tackle these issues. In this study, the potential of carboxymethyl chitosan (CMCS) and quaternary ammonium chitosan (TMC)-coated liposomes (CMCS/TMC-LPs) for improving the oral delivery capacity of curcumin (CUR) was explored. CMCS/TMC-LPs were prepared by electrostatic adsorption in a layer-by-layer manner. CMCS/...
27 CitationsSource