Hossein Motedayyen
Kashan University of Medical Sciences
GeneGenotypePeripheral blood mononuclear cellAmniotic epithelial cellsSingle-nucleotide polymorphismAntibodyProinflammatory cytokineAndrologyReceptorTumor necrosis factor alphaAlleleChemistryHaplotypeImmunologyInflammationCytokineLipopolysaccharideBasal cell carcinomaDiseasePeriodontitisPathogenesisStem cellIn patientCancer researchFlow cytometryMedicineBiologyImmune system
30Publications
6H-index
151Citations
Publications 31
Newest
#1Marzieh Heidarzadeh Arani (KAUMS: Kashan University of Medical Sciences)H-Index: 4
#2Atena Ramezanali Yakhchali (Shahid Beheshti University of Medical Sciences and Health Services)
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
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#1Nasrin Sereshki (IUMS: Isfahan University of Medical Sciences)H-Index: 3
#2Alireza Andalib (IUMS: Isfahan University of Medical Sciences)H-Index: 12
Last. David Wilkinson (Aberd.: University of Aberdeen)H-Index: 3
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Objective The maternal immune response to paternal antigens is induced at insemination. We believe that pregnancy protective alloantibodies, such as anti-paternal cytotoxic antibody (APCA), may be produced against the paternal antigens in the context of stimulated immunity at insemination and that they increase during pregnancy. APCA is necessary for pregnancy. It is directed towards paternal human leucocyte antigens (HLAs) and has cytotoxic activity against paternal leucocytes. The present stud...
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#1Reza ArefNezhad (Shiraz University of Medical Sciences)H-Index: 4
#2Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
Last. Ali Mohammadi (IAU: Islamic Azad University)H-Index: 50
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Multiple sclerosis (MS) is an inflammatory disease of central nervous system (CNS). The mmune system plays an important role in its pathogenesis. Current treatments are unable to cure patients and prevent the progression of MS lesions. Stem cell-based cell therapy has opened a new window for MS treatment. Stem cells regulate immune responses and improve axonal remyelination. Stem cells can be obtained from different origins such as embryonic, neural, bone marrow, and adipose tissues. But yet the...
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#1Mandana SattariH-Index: 10
#2Somayeh GhotlooH-Index: 5
Last. Hossein MotedayyenH-Index: 6
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#1Farshid Fathi (IUMS: Isfahan University of Medical Sciences)H-Index: 7
#2Batool Zamani (KAUMS: Kashan University of Medical Sciences)H-Index: 4
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
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#1Mahshid Rahmati (UI: University of Isfahan)
#2Seyed Mostafa Ghannadian (IUMS: Isfahan University of Medical Sciences)H-Index: 1
Last. Nahid Eskandari (IUMS: Isfahan University of Medical Sciences)H-Index: 10
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ABSTRACTThe presence of Th17 cells in CNS lesion of MS patients due to their inflammatory cytokines secretion is in line with the deterioration of the disease. Currently, the use of natural compoun...
3 CitationsSource
#1Ramin Sami (UI: University of Isfahan)H-Index: 6
#2Farshid Fathi (IUMS: Isfahan University of Medical Sciences)H-Index: 7
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
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Abstract Background Immunodeficiency has pivotal role in the pathogenesis of coronavirus disease 2019 (COVID-19). Several studies have indicated defects in the immune system of COVID-19 patients at different disease stages. Therefore, this study investigated whether alters in immune responses of COVID-19 patients may be considered as predicting factors for disease outcome. Methods The percentages of innate and adoptive immune cells in the recovered and dead patients with COVID-19, and healthy su...
5 CitationsSource
#1Farshid Fathi (IUMS: Isfahan University of Medical Sciences)H-Index: 7
#2Batool Zamani (KAUMS: Kashan University of Medical Sciences)H-Index: 4
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
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Programmed death-1 (PD-1), as an immunoinhibitory receptor encoded by programmed cell death-1 (PDCD1) gene, has a pivotal role in tolerance to self-antigens. Mutations of PDCD1 may participate in susceptibility to basal cell carcinoma (BCC) as the most common of skin cancer. We studied the impacts of two single nucleotide polymorphisms (SNPs) within PDCD1 and their haplotypes in BCC susceptibility in an Iranian population. The blood samples were collected from 210 BCC and 220 healthy individuals...
1 CitationsSource
#1Marzieh Heidarzadeh Arani (KAUMS: Kashan University of Medical Sciences)H-Index: 4
#2Reza ArefNezhad (Shiraz University of Medical Sciences)H-Index: 4
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
view all 5 authors...
Ataxia-telangiectasia (A-T) is known as an uncommon autosomal recessive disorder associated with recurrent infections and other clinical complications. The management of its complications can improve life quality of patients.
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#1Marziyeh Heidarzadeh Arani (KAUMS: Kashan University of Medical Sciences)
#2Mohsen Razavizadeh (KAUMS: Kashan University of Medical Sciences)H-Index: 3
Last. Hossein Motedayyen (KAUMS: Kashan University of Medical Sciences)H-Index: 6
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SIgMD is a rare immune disorder that occurs in a primary or secondary condition. Patients with recurrent infectious, cancers, and autoimmune disorders should be investigated to determine SIgMD.
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