Abraham Ajayi
Nigerian Institute of Medical Research
SerotypeDrug resistanceEffluxImmunologyGeographyNalidixic acidPseudomonas aeruginosaCefotaximeDiseaseImipenemAmoxicillinCloxacillinCholeraSalmonellaVeterinary medicineAntibioticsBiofilmMedicineBiologyMicrobiologyAntibiotic resistance
22Publications
4H-index
41Citations
Publications 19
Newest
#1Stella I. SmithH-Index: 21
#2Abraham AjayiH-Index: 4
Last. Mohamed AlboraieH-Index: 9
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#1Abraham Ajayi (Nigerian Institute of Medical Research)H-Index: 4
#2Tolulope Jolaiya (University of Lagos)H-Index: 2
Last. Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
view all 3 authors...
OBJECTIVE Prompt diagnosis of Helicobacter pylori infection is essential for proper treatment and eradication of the pathogen because prolonged infection could lead to gastric cancer. Sensitive and cost effective diagnostic methods are key to guiding treatment options that will reduce mortality. This study was aimed at detecting H. pylori from biopsies of peptic ulcer patients. Real-time PCR using TaqMan and EvaGreen assays targeting 16S rRNA and ureA genes were used to detect H. pylori DNA extr...
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#1Stella I. SmithH-Index: 21
#2Abraham AjayiH-Index: 4
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#1Elizabeth Tolulope Olubisose (University of Lagos)
#2Abraham Ajayi (Nigerian Institute of Medical Research)H-Index: 4
Last. Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
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Background Multidrug resistance efflux pumps and biofilm formation are mechanisms by which bacteria can evade the actions of many antimicrobials. Antibiotic resistant non-typhoidal Salmonella serovars have become wide spread causing infections that result in high morbidity and mortality globally. The aim of this study was to evaluate the efflux pump activity and biofilm forming capability of multidrug resistant non-typhoidal Salmonella (NTS) serovars isolated from food handlers and animals (catt...
1 CitationsSource
#1Florence Chijindu Ugwuanyi (University of Lagos)
#2Abraham Ajayi (Nigerian Institute of Medical Research)H-Index: 4
Last. Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
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BACKGROUND: Pseudomonas aeruginosa an opportunistic pathogen, is widely associated with nosocomial infections and exhibits resistance to multiple classes of antibiotics. The aim of this study was to determine the antibiotic resistance profile, biofilm formation and efflux pump activity of Pseudomonas strains isolated from clinical samples in Abeokuta Ogun state Nigeria. METHODS: Fifty suspected Pseudomonas isolates were characterized by standard biochemical tests and PCR using Pseudomonas specie...
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#1Abraham Ajayi (Nigerian Institute of Medical Research)H-Index: 4
#2Tolulope Jolaiya (University of Lagos)H-Index: 2
Last. Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
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The human gastrointestinal microbiota (GIM) is a complex and diverse ecosystem that consists of community of fungi, viruses, protists and majorly bacteria. The association of several human illnesses, such as inflammatory bowel disease, allergy, metabolic syndrome and cancers, have been linked directly or indirectly to compromise in the integrity of the GIM, for which some medical interventions have been proposed or attempted. This review highlights and gives update on various technologies, inclu...
2 CitationsSource
#1Dickson A. MusaH-Index: 1
#2Harun AremuH-Index: 1
Last. Stella I. SmithH-Index: 21
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The global evolution of antibiotic resistance has threatened the efficacy of available treatment options with ravaging impacts observed in developing countries. As a result, investigations into the prevalence of antibiotic resistance and the role of plasmids are crucial. In this study, we investigated the presence and distribution of blaTEM and gyrA genes, plasmid profiles, and the antimicrobial susceptibility pattern of Salmonella strains isolated from raw meat and stool sources across Niger St...
1 CitationsSource
#1Sharon Akinpelu (University of Lagos)
#2Abraham Ajayi (Nigerian Institute of Medical Research)H-Index: 4
Last. Adeyemi Isaac Adeleye (University of Lagos)H-Index: 1
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Nosocomial and community acquired multidrug resistant Klebsiella infections are wide spread resulting in high morbidity and mortality due to limited number of antibiotics treatment options. This study investigated efflux pump activity, biofilm forming potential and antibiotic susceptibility profile of Klebsiella spp. isolated from clinical samples in a tertiary hospital in Lagos Nigeria. Eighteen clinical Klebsiella spp. isolated from urine, blood and sputum were subjected to antibiotic suscepti...
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#1Abraham Ajayi (University of Lagos)H-Index: 4
#2Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
Last. Adeyemi Isaac Adeleye (University of Lagos)H-Index: 1
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Outbreaks of Salmonellosis remain a major public health problem globally. This study determined the diversity and antibiotic resistance gene profile of Salmonella enterica serovars isolated from hu...
1 CitationsSource
#1Abraham Ajayi (University of Lagos)H-Index: 4
#2Stella I. Smith (Nigerian Institute of Medical Research)H-Index: 21
: The original version of this article unfortunately contained a mistake. In the introduction, the infectious dose of Vibrio cholerae was written as 103-108 instead of 103-108 cells.
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