Eihab O. Bedawi
University of Oxford
Internal medicineRadiologySurgeryPathologyRetrospective cohort studyIntensive care medicineCytologyMalignant pleural effusionPleural diseasePleurodesisMesotheliomaEmpyemaThoracoscopyMalignancyMEDLINEPleural effusionPleural infectionPleural fluidIn patientThoracic ultrasoundMedicine
Publications 48
#1Eihab O. Bedawi (University of Oxford)H-Index: 5
#2Thomas Moore (University of Oxford)H-Index: 1
Last. Najib M. Rahman (University of Oxford)H-Index: 46
view all 6 authors...
A 45-year-old Caucasian woman was referred for investigation of recurrent chest infections. She had been treated over the previous 9 months for recurrent symptoms characterised by intermittent episodes of dyspnoea, cough productive of green sputum and pleuritic chest pain. Systemic enquiry was unremarkable; specifically, she had not experienced any weight loss or anorexia. On each episode, oxygen saturations were >94% and heart rate was <100 beats/min, with a single occurrence of a low-grade fev...
#1Christian B. Laursen (OUH: Odense University Hospital)H-Index: 13
#2Amelia O Clive (UoB: University of Bristol)H-Index: 13
Last. Nick A Maskell (UoB: University of Bristol)H-Index: 51
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Thoracic ultrasound is increasingly considered to be an essential tool for the pulmonologist. It is used in diverse clinical scenarios, including as an adjunct to clinical decision making for diagnosis, a real-time guide to procedures, and a predictor or measurement of treatment response. The aim of this European Respiratory Society task force was to produce a statement on thoracic ultrasound for pulmonologists using thoracic ultrasound within the field of respiratory medicine. The multidiscipli...
5 CitationsSource
#1Udit Chaddha (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 5
#2Abhinav Agrawal (Hofstra University)H-Index: 12
Last. Najib M. Rahman (University of Oxford)H-Index: 46
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Although our understanding of the pathogenesis of empyema has grown tremendously over the past few decades, questions still remain on how to optimally manage this condition. It has been almost a decade since the publication of the MIST2 trial, but there is still an extensive debate on the appropriate use of intrapleural fibrinolytic and deoxyribonuclease therapy in patients with empyema. Given the scarcity of overall guidance on this subject, we convened an international group of 22 experts from...
#1Eihab O. Bedawi (University of Oxford)H-Index: 5
#2Julien GuindeH-Index: 6
Last. Philippe Astoul (AMU: Aix-Marseille University)H-Index: 13
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Pleural infection and malignancy are among the most common causes of pleural disease and form the mainstay of pleural practice. There has been significant research and increase in scientific understanding in these areas in the past decade. With regard to pleural infection, the rising incidence remains worrying. An increased awareness allowing earlier diagnosis, earlier escalation of therapy and the use of validated risk stratification measures may improve outcomes. In pleural malignancy, researc...
#1Anand Sundaralingam (University of Oxford)H-Index: 1
#1Anand Sundaralingam (University of Oxford)H-Index: 2
Last. Najib M. Rahman (University of Oxford)H-Index: 46
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Pleural disease diagnostics represent a sprawling topic that has enjoyed a renaissance in recent years from humble beginnings. Whilst pleural patients are heterogeneous as a population and in the aetiology of the disease with which they present, we provide an overview of the typical diagnostic approach. Pleural fluid analysis is the cornerstone of the diagnostic pathway; however, it has many shortcomings. Strong cases have been made for more invasive upfront investigations, including image-guide...
1 CitationsSource
#1Maged HassanH-Index: 9
#2Radhika Banka (University of Oxford)H-Index: 1
Last. Najib M. RahmanH-Index: 46
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#2Rachelle AsciakH-Index: 7
Last. Ioannis PsallidasH-Index: 24
view all 21 authors...
Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpatient heterogeneity. A subset of the cells were subjected to high-throughput drug screening and coculture assays with cancer-specific cytotoxic T cells and showed diverse responses. Some of the biphasic...
3 CitationsSource