Luciana T. Young
Children's Memorial Hospital
StatisticsCorrelationInternal medicineSurgeryOdds ratioCardiologyRandomized controlled trialIntensive care medicinePhysical therapyPediatricsStandard scoreYoung adultCoarctation of the aortaAtenololThoracic aortaSupraventricular tachycardiaAortic aneurysmBody surface areaAtrial fibrillationTurner syndromeAortic dissectionElectrocardiographyHeart diseaseLosartanMarfan syndromeBicuspid aortic valvePopulationCARDIOVASCULAR MEASUREMENTSCause of deathSudden deathClinical careLarge sampleAmbulatoryIncidence (epidemiology)Medicine
Publications 5
#1Leo Lopez (Stanford University)H-Index: 19
#2Peter C. Frommelt (Children's Hospital of Wisconsin)H-Index: 37
Last. L. LuAnn Minich (UofU: University of Utah)H-Index: 47
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Background Different methods have resulted in variable Z scores for echocardiographic measurements. Using the measurements from 3,215 healthy North American children in the Pediatric Heart Network (PHN) echocardiographic Z score database, the authors compared the PHN model with previously published Z score models. Methods Z scores were derived for cardiovascular measurements using four models (PHN, Boston, Italy, and Detroit). Model comparisons were performed by evaluating (1) overlaid graphs of...
2 CitationsSource
#1Douglas Y. Mah (Boston Children's Hospital)H-Index: 14
#2Lynn A. Sleeper (Boston Children's Hospital)H-Index: 87
Last. Ronald V. Lacro (Boston Children's Hospital)H-Index: 32
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Patients with the Marfan syndrome (MFS) are at risk for sudden death. The contribution of arrhythmias is unclear. This study examines the prevalence of arrhythmias in children with the MFS and their relation to clinical and/or echocardiographic factors. Data from the Pediatric Heart Network randomized trial of atenolol versus losartan in MFS were analyzed (6 months to 25 years old, aortic root diameter z-score > 3.0, no previous aortic surgery and/or dissection). Baseline 24-hour ambulatory elec...
6 CitationsSource
#1Michael SilberbachH-Index: 26
Last. Luciana T. YoungH-Index: 4
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Girls and women with Turner syndrome face a lifelong struggle with both congenital heart disease and acquired cardiovascular conditions. Bicuspid aortic valve is common, and many have left-sided he...
26 CitationsSource
#1Ronald V. Lacro (Harvard University)H-Index: 32
#2Harry C. Dietz (Johns Hopkins University)H-Index: 108
Last. Lynn Mahony (UTSW: University of Texas Southwestern Medical Center)H-Index: 32
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BACKGROUND Aortic-root dissection is the leading cause of death in Marfan’s syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers. METHODS We conducted a randomized trial comparing losartan with atenolol in children and young adults with Marfan’s syndrome. The primary outcome was the rate of aorticroot enlargement, expressed as the change in the maximum aortic-root-diameter z ...
294 CitationsSource
#1Ronald V. LacroH-Index: 32
#2Harry C. DietzH-Index: 108
Last. Lynn MahonyH-Index: 32
view all 33 authors...
12 Citations