Jin Sook Kim
StereoisomerismCircular dichroismGlycationChemical structureChemistryAbsolute configurationAldose reductaseEthylenediaminetetraacetic acidLignanAldehyde ReductaseBiochemistryStereochemistry
Publications 5
#4Tae Joung Ha (RDA: Rural Development Administration)H-Index: 7
A new stereoisomer of 8-0-4' system neolignan, (7R,8S)-1-(3,4-dimethoxyphenyl)-2-[4-(3-hydroxy-1-propenyl)-2-methoxyphenoxy]-propane-1,3-diol (1) and a new stereoisomer of tetrahydrofuranoid lignan, (7R,8S,7'S,8'R)-(3,4,5,3',4')-pentamethoxy-9,7'-dihydroxy-8.8',7.O.9'-lignan (2) along with seven known lignans and neolignans (3-9) were isolated from the methanol extracts of the flower buds of Magnolia fargesii. The structures of these compounds (1-9) were elucidated by spectroscopic methods inclu...
#1Ji-Sook Lee (Daejeon University)H-Index: 18
#2In Sik Kim (Eulji University)H-Index: 17
Last. Chi-Young Yun (Daejeon University)H-Index: 13
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Abstract Ethnopharmacological relevance Houttuynia cordata Thunb (Saururaceae), known as ‘E-Sung-Cho’ in Korea, has been traditionally used for the treatment of herpes simplex, chronic sinusitis, and allergy. Aim of the study To investigate the inhibitory activity of Houttuynia cordata Thunb fractions (HcFs) on the T helper 2 (Th2) immune response, we evaluated the alternation of the release of Th2-type cytokines and chemokines such as interleukin (IL)-4 and IL-5, and thymus and activation-regul...
#1Nam Hee YooH-Index: 7
#2Dae Sik Jang (FDA: Food and Drug Administration)H-Index: 2
Last. Jin Sook Kim (FDA: Food and Drug Administration)H-Index: 5
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A novel 2,3-dioxygenated flavanone, erigeroflavanone (1), as well as eight known flavonoids and two known γ-pyranone derivatives, were isolated from an ethyl acetate-soluble extract of the flowers of Erigeron annuus. The structure of compound 1 was elucidated by interpretation of spectroscopic data. All of the isolates were subjected to in vitro bioassays to evaluate their inhibitory activity against advanced glycation end products formation and rat lens aldose reductase.
#1In Sik Kim (Eulji University)H-Index: 17
#2Joo-Hwan Kim (UPR-RP: UPRRP College of Natural Sciences)H-Index: 23
Last. Ji-Sook Lee (UPR-RP: UPRRP College of Natural Sciences)H-Index: 18
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Abstract Hottuynia cordata Thunb (Saururaceae; HC) is known as a therapeutic drug that has been used in traditional oriental medicine for the treatment of allergy. Mast cells play an important role in a variety of inflammatory diseases, and specifically asthma and atopy. In the present study, we investigated the effect of HC extracts on the migration of the human mast cell line, HMC-1, in response to stem cell factor (SCF). Treatment with HC extracts at a concentration of 10 μg/ml for 24 h showe...
#1Dae Sik JangH-Index: 2
#2Jong Min KimH-Index: 5
Last. Jin Sook KimH-Index: 5
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A new 2-arylbenzofuran, puerariafuran (1), as well as three known compounds, coumestrol (2), daidzein (3), and genistein (4), were isolated from a MeOH extract of the roots of Pueraria lobata as active constituents, using an in vitro bioassay based on the inhibition of advanced glycation end products (AGEs) to monitor chromatographic fractionation. The structure of 1 was determined by spectroscopic data interpretation, particularly by extensive 1D and 2D NMR studies. All the isolates (1—4) were ...
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